Study Of An NK-1 Anti-Emetic Medication For The Prevention Of Post-Operative Nausea And Vomiting In Female Patients



Status:Completed
Conditions:Hospital
Therapuetic Areas:Other
Healthy:No
Age Range:18 - 55
Updated:10/14/2017
Start Date:December 2004
End Date:July 2006

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Phase II Multicenter, Dose Ranging Study on the Safety and Antiemetic Efficacy of One Day Intraveous Dosing of GW597599 Administered With Ondansetron HCL in a Female Subjects Undergoing Surgical Procedures of High Emetogenic Risk

The purpose of this study is to determine the effectiveness of this medication in preventing
nausea and vomiting in female patients at risk for post-operative nausea and vomiting (PONV).

A Multicenter, Randomized, Double-blind, Double-dummy, Placebo-controlled, Parallel Group,
Phase II Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Oral (25 mg) and
Intravenous (3 mg and 18 mg) Formulations of the Neurokinin-1 Receptor Antagonist, GW597599,
When Administered with Intravenous Ondansetron Hydrochloride for the Prevention of
Post-operative Nausea and Vomiting and Post-discharge Nausea and Vomiting in Female Subjects
with Known Risk Factors for PONV Who are Undergoing Surgical Procedures Associated with an
Increased Emetogenic Risk

Inclusion Criteria:

- known risk factors for PONV.

- Undergoing gynecological or gallbladder surgery.
We found this trial at
17
sites
St Leonards, New South Wales 2065
7513
mi
from 91732
St Leonards,
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Albany, New York 12206
2438
mi
from 91732
Albany, NY
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Boca Raton, Florida 33486
2311
mi
from 91732
Boca Raton, FL
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Chicago, Illinois 60611
1730
mi
from 91732
Chicago, IL
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Dallas, Texas 75230
1223
mi
from 91732
Dallas, TX
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Durham, North Carolina 27705
2198
mi
from 91732
Durham, NC
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Glendale, California 91204
14
mi
from 91732
Glendale, CA
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Houston, Texas 77030
1357
mi
from 91732
Houston, TX
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Laguna Hills, California 92653
38
mi
from 91732
Laguna Hills, CA
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Little Rock, Arkansas 72205
1459
mi
from 91732
Little Rock, AR
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Los Angeles, California 90025
24
mi
from 91732
Los Angeles, CA
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New York, New York 10032
2435
mi
from 91732
New York, NY
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Omaha, Nebraska 68131
1299
mi
from 91732
Omaha, NE
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Pasadena, California 91105
9
mi
from 91732
Pasadena, CA
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Philadelphia, Pennsylvania 19104
2373
mi
from 91732
Philadelphia, PA
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Raleigh, North Carolina 27614
2217
mi
from 91732
Raleigh, NC
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Spokane, Washington 99208
947
mi
from 91732
Spokane, WA
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