Onset Motor Complications Using REQUIP CR (Ropinirole Controlled-release) As Add-on Therapy To L-dopa In Parkinson's



Status:Completed
Conditions:Parkinsons Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:30 - 70
Updated:10/14/2017
Start Date:December 2003
End Date:January 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Two Year Phase IIIb Randomised, Multicenter, Double-blind, SINEMET Controlled, Parallel Group, Flexible Dose Study, to Assess the Effectiveness of Controlled Release Ropinirole add-on Therapy to L-dopa at Increasing the Time to Onset of Dyskinesia in Parkinson's Disease Subjects.

This study evaluates how effective a new formulation of a marketed drug is in increasing the
time to onset of dyskinesia (abnormal twisting, writhing movements) in patients with
Parkinson's Disease who have been taking levodopa for less than 2 years.


Inclusion Criteria:

- Must be on 600mg or less of levodopa therapy for two years or less.

- Must be on a stable dose of levodopa therapy for at least 4 weeks prior to screening.

Exclusion Criteria:

- Current or past history of Dyskinesia.

- State of dementia or have a MMSE score < 26 at screening.
We found this trial at
65
sites
GSK Investigational Site
Madison, Wisconsin 53792
1654
mi
from 91732
Madison, WI
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GSK Investigational Site
Albany, New York 12206
2438
mi
from 91732
Albany, NY
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GSK Investigational Site
Alexandria, Virginia 22304
2277
mi
from 91732
Alexandria, VA
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GSK Investigational Site
Amherst, New York 14226
2185
mi
from 91732
Amherst, NY
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GSK Investigational Site
Anniston, Alabama 36207
1838
mi
from 91732
Anniston, AL
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GSK Investigational Site
Asheville, North Carolina 28803
2003
mi
from 91732
Asheville, NC
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GSK Investigational Site
Augusta, Georgia 30909
2053
mi
from 91732
Augusta, GA
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GSK Investigational Site
Austell, Georgia 30106
1904
mi
from 91732
Austell, GA
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GSK Investigational Site
Austin, Texas 78705
1211
mi
from 91732
Austin, TX
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GSK Investigational Site
Bingham Farms, Michigan 48025
1956
mi
from 91732
Bingham Farms, MI
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GSK Investigational Site
Birmingham, Alabama 35249
1777
mi
from 91732
Birmingham, AL
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GSK Investigational Site
Boca Raton, Florida 33486
2311
mi
from 91732
Boca Raton, FL
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GSK Investigational Site
Boise, Idaho 83712
665
mi
from 91732
Boise, ID
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GSK Investigational Site
Boulder, Colorado 80304
812
mi
from 91732
Boulder, CO
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GSK Investigational Site
Chapel Hill, North Carolina 27599
2194
mi
from 91732
Chapel Hill, NC
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GSK Investigational Site
Charleston, West Virginia 25304
2036
mi
from 91732
Charleston, WV
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GSK Investigational Site
Chicago, Illinois 60611
1730
mi
from 91732
Chicago, IL
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GSK Investigational Site
Cincinnati, Ohio 45229
1880
mi
from 91732
Cincinnati, OH
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GSK Investigational Site
Columbus, Georgia 31904
1901
mi
from 91732
Columbus, GA
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GSK Investigational Site
Dallas, Texas 75230
1223
mi
from 91732
Dallas, TX
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GSK Investigational Site
Danbury, Connecticut 06810
2458
mi
from 91732
Danbury, CT
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GSK Investigational Site
Decatur, Georgia 30033
1924
mi
from 91732
Decatur, GA
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GSK Investigational Site
Des Moines, Iowa 50314
1422
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from 91732
Des Moines, IA
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GSK Investigational Site
Edison, New Jersey
2412
mi
from 91732
Edison, NJ
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GSK Investigational Site
Elkridge, Maryland 21075
2296
mi
from 91732
Elkridge, MD
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GSK Investigational Site
Eugene, Oregon 97401
741
mi
from 91732
Eugene, OR
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GSK Investigational Site
Fort Lauderdale, Florida 33308
2315
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from 91732
Fort Lauderdale, FL
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GSK Investigational Site
Gainesville, Florida 32610
2105
mi
from 91732
Gainesville, FL
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GSK Investigational Site
Grand Rapids, Michigan 49546
1845
mi
from 91732
Grand Rapids, MI
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GSK Investigational Site
Hoffman Estates, Illinois 60194
1708
mi
from 91732
Hoffman Estates, IL
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GSK Investigational Site
Houston, Texas 77030
1357
mi
from 91732
Houston, TX
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GSK Investigational Site
Kansas City, Kansas 66160
1339
mi
from 91732
Kansas City, KS
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GSK Investigational Site
Kirkland, Washington 98034
967
mi
from 91732
Kirkland, WA
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GSK Investigational Site
La Jolla, California 92093
93
mi
from 91732
La Jolla, CA
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GSK Investigational Site
LaJolla, California 92037
96
mi
from 91732
LaJolla, CA
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GSK Investigational Site
Las Vegas, Nevada 89102
214
mi
from 91732
Las Vegas, NV
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GSK Investigational Site
Los Angeles, California 90025
24
mi
from 91732
Los Angeles, CA
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GSK Investigational Site
Lubbock, Texas 79410
924
mi
from 91732
Lubbock, TX
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GSK Investigational Site
Medford, Oregon 97504
628
mi
from 91732
Medford, OR
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GSK Investigational Site
Miami, Florida 33136
2321
mi
from 91732
Miami, FL
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GSK Investigational Site
Newark, Delaware 19713
2347
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from 91732
Newark, DE
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GSK Investigational Site
Newport Beach, California 92663
31
mi
from 91732
Newport Beach, CA
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GSK Investigational Site
Northbrook, Illinois 60062
1722
mi
from 91732
Northbrook, IL
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GSK Investigational Site
Oxnard, California 93030
66
mi
from 91732
Oxnard, CA
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GSK Investigational Site
Palm Beach Gardens, Florida 33410
2297
mi
from 91732
Palm Beach Gardens, FL
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GSK Investigational Site
Pembroke Pines, Florida 33028
2306
mi
from 91732
Pembroke Pines, FL
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GSK Investigational Site
Philadelphia, Pennsylvania 19104
2373
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from 91732
Philadelphia, PA
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GSK Investigational Site
Phoenix, Arizona 85012
343
mi
from 91732
Phoenix, AZ
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GSK Investigational Site
Port Charlotte, Florida 33952
2181
mi
from 91732
Port Charlotte, FL
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GSK Investigational Site
Raleigh, North Carolina 27614
2217
mi
from 91732
Raleigh, NC
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GSK Investigational Site
Richmond, Virginia 23298
2269
mi
from 91732
Richmond, VA
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GSK Investigational Site
Roanoke, Virginia 24013
2134
mi
from 91732
Roanoke, VA
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GSK Investigational Site
Rochester, New York 14642
2244
mi
from 91732
Rochester, NY
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GSK Investigational Site
San Antonio, Texas 78258
1184
mi
from 91732
San Antonio, TX
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GSK Investigational Site
San Jose, California 95116
312
mi
from 91732
San Jose, CA
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GSK Investigational Site
Seattle, Washington 98109
963
mi
from 91732
Seattle, WA
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GSK Investigational Site
South Weymouth, Massachusetts
2584
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from 91732
South Weymouth, MA
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GSK Investigational Site
Sun City, Arizona 85351
330
mi
from 91732
Sun City, AZ
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GSK Investigational Site
Tacoma, Washington 98405
939
mi
from 91732
Tacoma, WA
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GSK Investigational Site
Tampa, Florida 33612
2134
mi
from 91732
Tampa, FL
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GSK Investigational Site
Traverse City, Michigan 49684
1864
mi
from 91732
Traverse City, MI
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GSK Investigational Site
Tucson, Arizona 85724
427
mi
from 91732
Tucson, AZ
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GSK Investigational Site
Walnut Creek, California 94596
345
mi
from 91732
Walnut Creek, CA
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GSK Investigational Site
West Yarmouth, Massachusetts 02673
2623
mi
from 91732
West Yarmouth, MA
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GSK Investigational Site
Winston-Salem, North Carolina 27103
2122
mi
from 91732
Winston-Salem, NC
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