Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Partial Seizures



Status:Completed
Conditions:Neurology, Neurology, Neurology, Epilepsy
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:13 - Any
Updated:10/14/2017
Start Date:October 2004
End Date:July 2007

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Trial Summary
Trial Overview
Inclusion Criteria

A Multicenter, Double-Blind, Randomized, Parallel-group Evaluation of LAMICTAL Extended-release Adjunctive Therapy in Subjects With Partial Seizures

This study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine)
extended-release with placebo in the treatment of partial seizures. LAMICTAL extended-release
is an investigational drug. Placebo tablets look like LAMICTAL extended-release tablets but
do not contain active medication. In this study, LAMICTAL extended-release or placebo tablets
will be added to current seizure treatments.


Inclusion criteria:

- Diagnosis of epilepsy with partial seizures for more than 24 weeks.

- Must experience at least 8 partial seizures during an 8-week Baseline Phase.

- Must currently be receiving treatment with a stable regimen of one or two
antiepileptic drugs for at least four weeks.

- Patient or parent/caregiver must be willing and able to maintain a written daily
seizure diary.

Exclusion criteria:

- Previous treatment with lamotrigine.

- Exhibits any primary generalized seizures.

- Receiving treatment with felbamate or currently following the ketogenic diet.

- Pregnant, breastfeeding, or planning to become pregnant.
We found this trial at
64
sites
GSK Investigational Site
Seattle, Washington 98109
2007
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from 43215
Seattle, WA
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GSK Investigational Site
Anniston, Alabama 36207
462
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from 43215
Anniston, AL
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GSK Investigational Site
Asheville, North Carolina 28803
304
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from 43215
Asheville, NC
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GSK Investigational Site
Atlanta, Georgia 30341
424
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from 43215
Atlanta, GA
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GSK Investigational Site
Augusta, Georgia 30909
452
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from 43215
Augusta, GA
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GSK Investigational Site
Austell, Georgia 30106
434
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from 43215
Austell, GA
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GSK Investigational Site
Birmingham, Alabama 35249
493
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from 43215
Birmingham, AL
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GSK Investigational Site
Boston, Massachusetts 02115
643
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from 43215
Boston, MA
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GSK Investigational Site
Capital Federal, Buenos Aires
5386
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from 43215
Capital Federal,
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GSK Investigational Site
Chapel Hill, North Carolina 27599
353
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from 43215
Chapel Hill, NC
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GSK Investigational Site
Chesterfield, Missouri 63017
411
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from 43215
Chesterfield, MO
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GSK Investigational Site
Cheswick, Pennsylvania 15024
174
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from 43215
Cheswick, PA
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GSK Investigational Site
Chicago, Illinois 60611
274
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from 43215
Chicago, IL
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GSK Investigational Site
Columbus, Ohio 43219
7
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from 43215
Columbus, OH
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GSK Investigational Site
Crestview Hills, Kentucky 41017
105
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from 43215
Crestview Hills, KY
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GSK Investigational Site
Dallas, Texas 75230
905
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from 43215
Dallas, TX
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GSK Investigational Site
Des Moines, Iowa 50314
565
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from 43215
Des Moines, IA
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GSK Investigational Site
Detroit, Michigan 48202
165
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from 43215
Detroit, MI
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GSK Investigational Site
Edison, New Jersey
455
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from 43215
Edison, NJ
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GSK Investigational Site
Flossmoor, Illinois 60422
267
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from 43215
Flossmoor, IL
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GSK Investigational Site
Galveston, Texas 77555
992
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from 43215
Galveston, TX
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GSK Investigational Site
Grand Rapids, Michigan 49546
242
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from 43215
Grand Rapids, MI
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GSK Investigational Site
Greensburg, Pennsylvania 15601
185
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from 43215
Greensburg, PA
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GSK Investigational Site
Greenville, North Carolina 27858
430
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from 43215
Greenville, NC
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GSK Investigational Site
Hollywood, Florida 33021
977
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from 43215
Hollywood, FL
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GSK Investigational Site
Houston, Texas 77030
995
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from 43215
Houston, TX
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GSK Investigational Site
Kansas City, Missouri 64128
616
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from 43215
Kansas City, MO
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GSK Investigational Site
Las Vegas, Nevada 89102
1759
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from 43215
Las Vegas, NV
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GSK Investigational Site
Lexington, Kentucky 40504
156
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from 43215
Lexington, KY
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GSK Investigational Site
Little Rock, Arkansas 72205
625
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from 43215
Little Rock, AR
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GSK Investigational Site
Los Angeles, California 90025
1983
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from 43215
Los Angeles, CA
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GSK Investigational Site
Louisville, Kentucky 40202
188
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from 43215
Louisville, KY
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GSK Investigational Site
Maitland, Florida 32751
788
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from 43215
Maitland, FL
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GSK Investigational Site
Mesa, Arizona 85206
1644
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from 43215
Mesa, AZ
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GSK Investigational Site
Milwaukee, Wisconsin 53215
329
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from 43215
Milwaukee, WI
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GSK Investigational Site
Minneapolis, Minnesota 55404
624
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from 43215
Minneapolis, MN
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GSK Investigational Site
New York, New York 10032
481
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from 43215
New York, NY
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GSK Investigational Site
Newport Beach, California 92663
1967
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from 43215
Newport Beach, CA
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GSK Investigational Site
Northport, Alabama 35476
529
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from 43215
Northport, AL
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GSK Investigational Site
Ocala, Florida 34471
748
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from 43215
Ocala, FL
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GSK Investigational Site
Oklahoma City, Oklahoma 73112
851
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Oklahoma City, OK
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GSK Investigational Site
Philadelphia, Pennsylvania 19104
414
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from 43215
Philadelphia, PA
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GSK Investigational Site
Phoenix, Arizona 85012
1660
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from 43215
Phoenix, AZ
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GSK Investigational Site
Plainview, New York 11803
505
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from 43215
Plainview, NY
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GSK Investigational Site
Raleigh, North Carolina 27614
366
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from 43215
Raleigh, NC
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GSK Investigational Site
Richmond, Virginia 23298
344
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from 43215
Richmond, VA
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GSK Investigational Site
Salt Lake City, Utah 84132
1511
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from 43215
Salt Lake City, UT
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GSK Investigational Site
San Antonio, Texas 78258
1126
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San Antonio, TX
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GSK Investigational Site
Santa Monica, California 90404
1984
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from 43215
Santa Monica, CA
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GSK Investigational Site
Savannah, Georgia 31405
557
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Savannah, GA
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GSK Investigational Site
Scottsdale, Arizona 85259
1644
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Scottsdale, AZ
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GSK Investigational Site
Sepuldeva, California 91343
?
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Sepuldeva, CA
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GSK Investigational Site
Springfield, Illinois 62702
349
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Springfield, IL
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GSK Investigational Site
St. Louis, Missouri 63110
397
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St. Louis, MO
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GSK Investigational Site
Sun City, Arizona 85351
1669
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Sun City, AZ
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GSK Investigational Site
Tallahassee, Florida 32308
658
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Tallahassee, FL
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GSK Investigational Site
Tampa, Florida 33612
823
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Tampa, FL
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GSK Investigational Site
Traverse City, Michigan 49684
356
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Traverse City, MI
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GSK Investigational Site
Tucson, Arizona 85724
1639
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Tucson, AZ
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GSK Investigational Site
Tuscaloosa, Alabama 35401
534
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Tuscaloosa, AL
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GSK Investigational Site
Washington, District of Columbia 20007
328
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Washington,
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GSK Investigational Site
West Orange, New Jersey 07052
465
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West Orange, NJ
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GSK Investigational Site
Wichita, Kansas 67207
780
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Wichita, KS
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GSK Investigational Site
Wichita Falls, Texas 76310
949
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Wichita Falls, TX
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