Evaluation of Major Cardiovascular Events in Patients With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo



Status:Recruiting
Conditions:Peripheral Vascular Disease
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 85
Updated:3/23/2019
Start Date:December 2016
End Date:March 2022
Contact:Maggie Horner, BA, MBA
Email:clinicaltrials@esperion.com
Phone:734-887-3903

Use our guide to learn which trials are right for you!

A Randomized, Double-blind, Placebo-controlled Study to Assess the Effects of Bempedoic Acid (ETC-1002) on the Occurrence of Major Cardiovascular Events in Patients With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant

The purpose of this study is to determine if treatment with bempedoic acid (ETC-1002) versus
placebo decreases the risk of cardiovascular events in patients who are statin intolerant.


Inclusion Criteria:

- Age between 18 and 85 years

- History of, or at high risk for, cardiovascular disease (CVD) including coronary
artery disease, symptomatic peripheral arterial disease, cerebrovascular
atherosclerotic disease, or at high risk for a cardiovascular event

- Patient reported history of statin intolerance (inability to tolerate 2 or more
statins, one at a low dose)

- Men and nonpregnant, nonlactating women

- Fasting blood LDL-cholesterol ≥ 100 (2.6 mmol/L) at screening

Exclusion Criteria:

- Fasting blood triglycerides greater than 500 mg/dL (5.6 mmol/L) at screening

- Recent (within 90 days of screening) history of major cardiovascular events, transient
ischemic attack (TIA), or unstable or symptomatic cardiac arrhythmia

- History of severe heart failure

- Uncontrolled hypertension or uncontrolled diabetes
We found this trial at
265
sites
?
mi
from
Gainesville, GA
Click here to add this to my saved trials
?
mi
from
Abington, PA
Click here to add this to my saved trials
?
mi
from
Akron, OH
Click here to add this to my saved trials
?
mi
from
Albany, NY
Click here to add this to my saved trials
?
mi
from
Allen, TX
Click here to add this to my saved trials
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
Amarillo, Texas 79106
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
?
mi
from
Anderson, IN
Click here to add this to my saved trials
?
mi
from
Anderson, SC
Click here to add this to my saved trials
?
mi
from
Annapolis, MD
Click here to add this to my saved trials
?
mi
from
Asheboro, NC
Click here to add this to my saved trials
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Austin, Texas 78705
?
mi
from
Austin, TX
Click here to add this to my saved trials
?
mi
from
Bahia Blanca,
Click here to add this to my saved trials
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
?
mi
from
Beaver, PA
Click here to add this to my saved trials
?
mi
from
Bellevue, WA
Click here to add this to my saved trials
Beverly Hills, California 90211
?
mi
from
Beverly Hills, CA
Click here to add this to my saved trials
?
mi
from
Binghamton, NY
Click here to add this to my saved trials
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
?
mi
from
Boynton Beach, FL
Click here to add this to my saved trials
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
?
mi
from
Bridgeton, MO
Click here to add this to my saved trials
?
mi
from
Bridgeton, NJ
Click here to add this to my saved trials
?
mi
from
Bridgewater, NJ
Click here to add this to my saved trials
?
mi
from
Bronxville, NY
Click here to add this to my saved trials
?
mi
from
Buckley, MI
Click here to add this to my saved trials
?
mi
from
Buffalo, NY
Click here to add this to my saved trials
?
mi
from
Burke, VA
Click here to add this to my saved trials
Burlington, North Carolina 27215
?
mi
from
Burlington, NC
Click here to add this to my saved trials
?
mi
from
Cadillac, MI
Click here to add this to my saved trials
?
mi
from
Camp Hill, PA
Click here to add this to my saved trials
?
mi
from
Canton, OH
Click here to add this to my saved trials
?
mi
from
Carlsbad, CA
Click here to add this to my saved trials
?
mi
from
Caro, MI
Click here to add this to my saved trials
Cary, North Carolina 27518
?
mi
from
Cary, NC
Click here to add this to my saved trials
?
mi
from
Cary, NC
Click here to add this to my saved trials
?
mi
from
Champaign, IL
Click here to add this to my saved trials
?
mi
from
Chandler, AZ
Click here to add this to my saved trials
Charleston, South Carolina 29412
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charlotte, North Carolina 28207
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
?
mi
from
Chicago, IL
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Clearwater, FL
Click here to add this to my saved trials
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Colorado Springs, Colorado 80910
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
?
mi
from
Columbia, MD
Click here to add this to my saved trials
?
mi
from
Columbus, GA
Click here to add this to my saved trials
?
mi
from
Columbus, OH
Click here to add this to my saved trials
?
mi
from
Cottonwood, AZ
Click here to add this to my saved trials
?
mi
from
Council Bluffs, IA
Click here to add this to my saved trials
?
mi
from
Covington, GA
Click here to add this to my saved trials
?
mi
from
Crystal River, FL
Click here to add this to my saved trials
?
mi
from
Cumberland, RI
Click here to add this to my saved trials
?
mi
from
Cumming, GA
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
?
mi
from
Danville, VA
Click here to add this to my saved trials
?
mi
from
Dayton, OH
Click here to add this to my saved trials
?
mi
from
Desoto, TX
Click here to add this to my saved trials
?
mi
from
Dunwoody, GA
Click here to add this to my saved trials
?
mi
from
Elizabethtown, KY
Click here to add this to my saved trials
?
mi
from
Elkhart, IN
Click here to add this to my saved trials
?
mi
from
Endwell, NY
Click here to add this to my saved trials
?
mi
from
Eunice, LA
Click here to add this to my saved trials
?
mi
from
Evansville, IN
Click here to add this to my saved trials
?
mi
from
Falls Church, VA
Click here to add this to my saved trials
?
mi
from
Fargo, ND
Click here to add this to my saved trials
?
mi
from
Farmington, UT
Click here to add this to my saved trials
?
mi
from
Fayetteville, TN
Click here to add this to my saved trials
?
mi
from
Fleming Island, FL
Click here to add this to my saved trials
?
mi
from
Flemington, NJ
Click here to add this to my saved trials
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
?
mi
from
Fountain Hills, AZ
Click here to add this to my saved trials
420 West 12th Avenue
Franklin, Ohio 43210
?
mi
from
Franklin, OH
Click here to add this to my saved trials
?
mi
from
Fremont, NE
Click here to add this to my saved trials
?
mi
from
Gilbert, AZ
Click here to add this to my saved trials
?
mi
from
Glendale, AZ
Click here to add this to my saved trials
?
mi
from
Golden, CO
Click here to add this to my saved trials
?
mi
from
Grand Blanc, MI
Click here to add this to my saved trials
?
mi
from
Grand Rapids, MI
Click here to add this to my saved trials
?
mi
from
Green Acres, FL
Click here to add this to my saved trials
?
mi
from
Green Bay, WI
Click here to add this to my saved trials
?
mi
from
Greeneville, TN
Click here to add this to my saved trials
Greensboro, North Carolina 27401
?
mi
from
Greensboro, NC
Click here to add this to my saved trials
Greensboro, North Carolina 27408
?
mi
from
Greensboro, NC
Click here to add this to my saved trials
?
mi
from
Greer, SC
Click here to add this to my saved trials
?
mi
from
Gurnee, IL
Click here to add this to my saved trials
?
mi
from
Haddon, NJ
Click here to add this to my saved trials
?
mi
from
Hamden, CT
Click here to add this to my saved trials
?
mi
from
Hampton, VA
Click here to add this to my saved trials
?
mi
from
Hartford, CT
Click here to add this to my saved trials
?
mi
from
Haverhill, MA
Click here to add this to my saved trials
?
mi
from
Henderson, NV
Click here to add this to my saved trials
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
Hickory, North Carolina 28602
?
mi
from
Hickory, NC
Click here to add this to my saved trials
?
mi
from
Hickory, NC
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials