Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry



Status:Recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:8/16/2018
Start Date:February 1, 2017
End Date:August 1, 2019
Contact:Zhaoyang Fan, PhD
Email:zhaoyang.fan@cshs.org
Phone:310 248-8661

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This is a new vessel wall imaging-based stroke registry which will investigate the clinical
utility of the whole-brain intracranial vessel wall Magnetic Resonance Imaging (MRI)
technique in assessing the etiologies in patients with ischemic stroke.

The registry will focus on investigating the utility of whole-brain vessel wall MRI
techniques in assessing the etiologies in patients with recent ischemic stroke. Patients who
have had ischemic stroke (as confirmed by diffusion weighted MRI) and have had or will
undergo 3D whole-brain vessel wall MRI within 8 weeks of symptom onset will be recruited into
this study. It is anticipated that a total of 1000 subjects will be recruited from Feb 2017
to Feb 2019. Approximately 12 centers in the US and China will participate in the registry.
MRI whole-brain vessel wall images will be analyzed for detection and characteristics of
various vessel wall pathologies and association between vessel wall imaging findings and
patient's clinical information.

Inclusion Criteria:

- Male or female ≥ 18 years of age

- Ischemic stroke onset within 8 weeks and confirmed by diffusion weighted MRI

- Ability to read and understand informed consent

Exclusion Criteria:

- The cause of stroke has been confirmed to be related to cardiac or extracranial
carotid or aorta pathologies.

- Contraindications to MR imaging including mechanically, magnetically, or electrically
activated implants, ferromagnetic implants and ferromagnetic foreign bodies,
pregnancy.

- Inability to tolerate MRI imaging secondary to an inability to lie supine or severe
claustrophobia.

- Non-compliant with visit instructions, including inability to lie still, hold breath
or follow procedure instructions
We found this trial at
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45 Gongchen Street
Beijiang, 10008
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
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Torrance, California 90505
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Torrance, CA
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