Listening to Mom in the NICU: Neural, Clinical and Language Outcomes
| Status: | Recruiting |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/6/2019 |
| Start Date: | July 2016 |
| End Date: | December 31, 2019 |
| Contact: | Katherine E Travis, PhD |
| Email: | ktravis1@stanford.edu |
| Phone: | 650-498-7690 |
Listening to Mom in the Neonatal Intensive Care Unit (NICU): Neural, Clinical and Language Outcomes
The purpose of this study is to examine whether playing recordings of a mother's voice to her
infant while in the hospital nursery is an effective treatment for promoting healthy brain
and language development in infants born preterm.
infant while in the hospital nursery is an effective treatment for promoting healthy brain
and language development in infants born preterm.
Children born preterm are at-risk for developmental language delays. Language problems in
preterm children are thought to be related to neurobiological factors, including injuries to
white matter structures of the brain and environmental factors, including decreased exposure
to maternal speech in the hospital nursery. There is evidence to suggest that maternal speech
input may be important for promoting healthy brain and language development.
Participants will be randomly assigned to one of two study groups. Each infant has a 50%
chance of being assigned to the group that will listen to a recording of his/her mother's
voice and a 50% chance of being assigned to the group that will not be played a voice
recording. Mother's of participating infants will have her voice recorded as she reads a
common children's storybook. Recordings will be played to infants each day until s/he is
discharged from the hospital. Participation in this study requires that all infants receive
up to an additional 10 minutes of brain scans as part of his/her routine clinical magnetic
resonance imaging (MRI).
preterm children are thought to be related to neurobiological factors, including injuries to
white matter structures of the brain and environmental factors, including decreased exposure
to maternal speech in the hospital nursery. There is evidence to suggest that maternal speech
input may be important for promoting healthy brain and language development.
Participants will be randomly assigned to one of two study groups. Each infant has a 50%
chance of being assigned to the group that will listen to a recording of his/her mother's
voice and a 50% chance of being assigned to the group that will not be played a voice
recording. Mother's of participating infants will have her voice recorded as she reads a
common children's storybook. Recordings will be played to infants each day until s/he is
discharged from the hospital. Participation in this study requires that all infants receive
up to an additional 10 minutes of brain scans as part of his/her routine clinical magnetic
resonance imaging (MRI).
Inclusion Criteria:
- Infants born preterm at Stanford Children's Hospital between 27 0/7 - 31 6/7 weeks
gestational age
Exclusion Criteria:
- Congenital anomalies
- Recognizable malformation syndromes
- Active seizure disorders
- History of Central Nervous System infections
- Hydrocephalus
- Major sensori-neural hearing loss
- Likelihood to be transferred from NICU to alternate care facility or home environment
prior to 36 weeks PMA
- Intraventricular Hemorrhage Grades III-IV
- Cystic periventricular leukomalacia (PVL)
- Surgical treatment for necrotizing enterocolitis
- Small for gestational age (SGA) <3 percentile and/or Intra-uterine growth restriction
(IUGR) no head sparing
- Twin-to-twin transfusions
We found this trial at
1
site
Palo Alto, California 94304
Principal Investigator: Katherine E Travis, PhD
Phone: 650-498-7690
Click here to add this to my saved trials
