Examination of Low Wattage and High Wattage E-Cigarettes

Inclusion Criteria:

1. smoke ≥5 cigarettes per day for the past year;

2. no quit attempt in the prior 3 months and no plan to quit in the next 3 months;

3. read, write, and speak in English;

4. report at least minimal interest in switching to an alternative product (> "not at
all" on a Likert scale);

5. never purchased or regularly used a tank system, mechanical mod, or advanced personal
vaporizer EC, though previous use of cig-a-like devices will be allowed but not in the
last 3 months;

6. plan to live in the local area for next year; and

7. have reliable means of transport. -

Exclusion Criteria:

1. <18 years old;

2. unstable or significant medical condition such as respiratory, kidney, or liver
disease that could potentially affect biomarker data;

3. unstable or significant psychiatric conditions (past and stable conditions will be
allowed);

4. history of cardiac event or distress within the past 3 months; and

5. currently pregnant, planning to become pregnant, or breastfeeding (n.b: pregnancy
status will continue to be evaluated throughout the study at each visit).