Regulation of Inflammatory Genes in Psoriasis
| Status: | Recruiting |
|---|---|
| Conditions: | Psoriasis |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 19 - 99 |
| Updated: | 5/11/2018 |
| Start Date: | April 22, 2014 |
| End Date: | April 28, 2020 |
Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory
changes in the skin. An extensive cytokine network including generated by activated dendritic
cells and T cells mediates the formation of psoriatic lesions. These immune-response
parameters can be used as markers in the severity and management of the disease after further
in-depth studies.
changes in the skin. An extensive cytokine network including generated by activated dendritic
cells and T cells mediates the formation of psoriatic lesions. These immune-response
parameters can be used as markers in the severity and management of the disease after further
in-depth studies.
Inclusion Criteria:
- Clinical diagnosis of psoriasis
- Must be age 19 or older.
- Must be Fitzpatrick skin type I, II, III, IV, V, VI.
Exclusion Criteria:
- Subjects who do not have photosensitive disease and are not on photosensitizing
medications.
- Subjects with a history of keloids (who are more likely to develop hypertrophic scars
following skin biopsy).
- Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
- Subjects who are pregnant.
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