A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1



Status:Terminated
Conditions:HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:6/21/2017
Start Date:July 21, 2004
End Date:July 16, 2005

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The main objective of this study is to compare the safety and efficacy of an enfuvirtide
containing regimen to a nucleoside combination regimen. Resistance information will also be
collected.


Inclusion Criteria:

- CD4 cell count greater than 50 cells/mm^3

- HIV-1 RNA viral load greater than or equal to 5000 copies/mL

- Patients must be HIV treatment experienced

- Patients diagnosed with HIV-1 infection

Exclusion Criteria:

- Female patients must not be able to have children or must be under effective
contraceptives

- Female patients who are pregnant

- Have taken enfuvirtide and/or T-1249 before

- Have serious kidney problems

- Alcohol and/or drug abuse

- Have had an organ transplant
We found this trial at
16
sites
2435
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New York, NY
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1919
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Atlanta, GA
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2301
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Baltimore, MD
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2578
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Boston, MA
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1729
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Chicago, IL
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1225
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Dallas, TX
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1838
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Hobson City, AL
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1357
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from 91732
Houston, TX
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Huntersville, North Carolina 28078
2099
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Huntersville, NC
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1609
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Jackson, MS
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13
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Los Angeles, CA
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1978
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Macon, GA
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2423
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Newark, NJ
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2182
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from 91732
Orlando, FL
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1573
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from 91732
Saint Louis, MO
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2281
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from 91732
Washington, D.C.,
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