Language in Primary Progressive Aphasia



Status:Recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:Any
Updated:7/27/2018
Start Date:May 2007
End Date:April 2023
Contact:Christina Coventry, MS, RN
Email:christina.coventry@northwestern.edu
Phone:312-908-9681

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The purpose of this study is to further define the neurological and linguistic deterioration
in primary progressive aphasia.

The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral,
anatomical and physiological changes in people with PPA throughout the course of the illness.
The researchers in this study want to increase awareness of PPA, educate others about this
unique disorder, and to encourage more research to eventually develop therapies.

During the three-day research program, participants will be asked to undergo
neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging
(MRI and PET), eyetracking experiments, and other computer and language testing batteries.
Participants may be asked to return every two years to complete the same measures.

For participants not living near Chicago, IL, flights and accommodations (for both the person
with PPA and their companion) will be covered by the study.

Inclusion Criteria:

- Diagnosis of primary progressive aphasia

- Right-handed

- English speaker

- Visual acuity of 20/30 corrected

- Adequate hearing to follow conversation

- Safe for an MRI scan

Exclusion Criteria:

- Left-handedness

- Claustrophobia

- Presence of significant medical illness that initially or in the future could
interfere with continued participation in the study
We found this trial at
1
site
303 East Superior Street
Chicago, Illinois 60611
Principal Investigator: M.-Marsel Mesulam, MD
Phone: 312-908-9681
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mi
from
Chicago, IL
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