A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults



Status:Completed
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 75
Updated:1/19/2019
Start Date:May 6, 2017
End Date:August 2, 2018

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-blind, Dose-finding Study to Evaluate the Change in Weight After 24 Weeks Treatment With 8 Doses of LIK066 Compared to Placebo in Obese or Overweight Adults, Followed by 24 Weeks Treatment With 2 Doses of LIK066 and Placebo

This is a dose-finding study to evaluate the change in weight after 24 weeks treatment with 8
different doses of LIK066 compared to placebo in obese or overweight adults, followed by 24
weeks treatment with 2 doses of LIK066 and placebo.


Inclusion Criteria:

1. informed consent

2. (BMI>=30) or (BMI>=27 with history of CV disease, hypertension, dyslipidemia,
pre-diabetes or type 2 diabetes mellitus, sleep-apnea syndrome)

3. willing to comply with life-style intervention and treatment during the full duration
of the study (approximately 54 weeks)

Exclusion Criteria:

- Hypersensitivity to any of the study medications

- Pregnancy or lactating women

- History of malignancies

- Use of pharmacologically active weight loss products

- Bariatric surgery

- Ketoacidosis, lactic acidosis, hyperosmolar coma in the 6 months before the screening
visit.

- HbA1c >10% at the screening visit.
We found this trial at
56
sites
Novartis Investigative Site
Golden, Colorado 80401
1174
mi
from 43215
Golden, CO
Click here to add this to my saved trials
Novartis Investigative Site
Anniston, Alabama 36207
462
mi
from 43215
Anniston, AL
Click here to add this to my saved trials
Novartis Investigative Site
Athens, Georgia 30606
416
mi
from 43215
Athens, GA
Click here to add this to my saved trials
Novartis Investigative Site
Augusta, Georgia 30904
451
mi
from 43215
Augusta, GA
Click here to add this to my saved trials
Novartis
Baltimore, Maryland 21287
345
mi
from 43215
Baltimore, MD
Click here to add this to my saved trials
Novartis Investigative Site
Baton Rouge, Louisiana 70808
802
mi
from 43215
Baton Rouge, LA
Click here to add this to my saved trials
Novartis Investigative Site
Beltsville, Maryland 20705
332
mi
from 43215
Beltsville, MD
Click here to add this to my saved trials
Novartis Investigative Site
Beverly Hills, California 90211
1979
mi
from 43215
Beverly Hills, CA
Click here to add this to my saved trials
Novartis Investigative Site
Bountiful, Utah 84010
1512
mi
from 43215
Bountiful, UT
Click here to add this to my saved trials
Novartis Investigative Site
Bradenton, Florida 32405
691
mi
from 43215
Bradenton, FL
Click here to add this to my saved trials
Novartis Investigative Site
Bronx, New York 10461
486
mi
from 43215
Bronx, NY
Click here to add this to my saved trials
Novartis Investigative Site
Carmichael, California 95608
2034
mi
from 43215
Carmichael, CA
Click here to add this to my saved trials
Novartis Investigative Site
Concord, California 94520
2083
mi
from 43215
Concord, CA
Click here to add this to my saved trials
Novartis Investigative Site
Covington, Louisiana 70433
767
mi
from 43215
Covington, LA
Click here to add this to my saved trials
Novartis
Denver, Colorado 80262
1159
mi
from 43215
Denver, CO
Click here to add this to my saved trials
Novartis Investigator Site
Evansville, Indiana 47713
280
mi
from 43215
Evansville, IN
Click here to add this to my saved trials
Novartis Investigative Site
Fort Lauderdale, Florida 33313
967
mi
from 43215
Fort Lauderdale, FL
Click here to add this to my saved trials
Novartis Investigative Site
Graz,
4617
mi
from 43215
Graz,
Click here to add this to my saved trials
Novartis Investigative Site
Gurnee, Illinois 60031
303
mi
from 43215
Gurnee, IL
Click here to add this to my saved trials
Novartis Investigative Site
Hammond, Louisiana 70403
776
mi
from 43215
Hammond, LA
Click here to add this to my saved trials
Novartis Investigative Site
Hickory, North Carolina 28601
306
mi
from 43215
Hickory, NC
Click here to add this to my saved trials
Novartis Investigative Site
Honolulu, Hawaii 96813
4501
mi
from 43215
Honolulu, HI
Click here to add this to my saved trials
Novartis Investigative Site
Houston, Texas 77030
995
mi
from 43215
Houston, TX
Click here to add this to my saved trials
Novartis Investigative Site
Indianapolis, Indiana 46202
167
mi
from 43215
Indianapolis, IN
Click here to add this to my saved trials
Novartis Investigative Site
Jasper, Alabama 35501
484
mi
from 43215
Jasper, AL
Click here to add this to my saved trials
Novartis Investigative Site
Kenosha, Wisconsin 53144
307
mi
from 43215
Kenosha, WI
Click here to add this to my saved trials
Novartis Investigative Site
Lansdale, Pennsylvania 19446
409
mi
from 43215
Lansdale, PA
Click here to add this to my saved trials
Novartis Investigative site
Los Angeles, California 90095
1982
mi
from 43215
Los Angeles, CA
Click here to add this to my saved trials
Novartis Investigative Site
Louisville, Kentucky 40202
188
mi
from 43215
Louisville, KY
Click here to add this to my saved trials
Novartis Investigative Site
Metairie, Louisiana 70006
795
mi
from 43215
Metairie, LA
Click here to add this to my saved trials
Novartis Investigative Site
Missoula, Montana 59808
1614
mi
from 43215
Missoula, MT
Click here to add this to my saved trials
Novartis Investigative Site
Moncks Corner, South Carolina 29461
496
mi
from 43215
Moncks Corner, SC
Click here to add this to my saved trials
319, Novartis Investigational Site
Mount Pleasant, South Carolina 29464
525
mi
from 43215
Mount Pleasant, SC
Click here to add this to my saved trials
Novartis Investigative Site
New Orleans, Louisiana 70115
798
mi
from 43215
New Orleans, LA
Click here to add this to my saved trials
Novartis
230 Park Avenue, 21st Floor
New York, New York 10169
1-888-669-6682)
Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
481
mi
from 43215
New York, NY
Click here to add this to my saved trials
Novartis Investigative Site
Newport News, Virginia 23606
404
mi
from 43215
Newport News, VA
Click here to add this to my saved trials
Novartis Investigative Site
Northridge, California 91325
1981
mi
from 43215
Northridge, CA
Click here to add this to my saved trials
Novartis Investigative Site
Omaha, Nebraska 68144
691
mi
from 43215
Omaha, NE
Click here to add this to my saved trials
Novartis
Pittsburgh, Pennsylvania 15224
165
mi
from 43215
Pittsburgh, PA
Click here to add this to my saved trials
Novartis Investigative Site
Port Charlotte, Florida 33952
898
mi
from 43215
Port Charlotte, FL
Click here to add this to my saved trials
Novartis Investigative Site
Renton, Washington 98055
2001
mi
from 43215
Renton, WA
Click here to add this to my saved trials
Novartis Investigative Site
Richmond, Virginia 23249
344
mi
from 43215
Richmond, VA
Click here to add this to my saved trials
Novartis Investigative Site
Roseville, California 95661
2028
mi
from 43215
Roseville, CA
Click here to add this to my saved trials
Novartis Investigative Site
Royal Oak, Michigan 48073
176
mi
from 43215
Royal Oak, MI
Click here to add this to my saved trials
Novartis Investigative Site
Saint Louis, Missouri 63128
406
mi
from 43215
Saint Louis, MO
Click here to add this to my saved trials
Novartis Investigative Site
Saint Peters, Missouri 63303
413
mi
from 43215
Saint Peters, MO
Click here to add this to my saved trials
Novartis Investigative Site
Salt Lake City, Utah 84103
1513
mi
from 43215
Salt Lake City, UT
Click here to add this to my saved trials
Novartis Investigative Site
San Ramon, California 94582
2084
mi
from 43215
San Ramon, CA
Click here to add this to my saved trials
Novartis Investigational Site
Springfield, Illinois 62703
350
mi
from 43215
Springfield, IL
Click here to add this to my saved trials
Novartis Investigative Site
Stockton, California 95204
2046
mi
from 43215
Stockton, CA
Click here to add this to my saved trials
Novartis Investigative Site
Summerville, South Carolina 29485
505
mi
from 43215
Summerville, SC
Click here to add this to my saved trials
Novartis Investigative Site
Tacoma, Washington 98405
2013
mi
from 43215
Tacoma, WA
Click here to add this to my saved trials
Novartis Investigative Site
Towson, Maryland 21204
341
mi
from 43215
Towson, MD
Click here to add this to my saved trials
Novartis Investigative Site
Walnut Creek, California 94598
2086
mi
from 43215
Walnut Creek, CA
Click here to add this to my saved trials
Novartis Investigative Site
Wauconda, Illinois 60084
309
mi
from 43215
Wauconda, IL
Click here to add this to my saved trials
Novartis Investigative Site
West Palm Beach, Florida 33407
927
mi
from 43215
West Palm Beach, FL
Click here to add this to my saved trials