Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue

Conditions:Cancer, Cancer, Cancer, Pancreatic Cancer
Therapuetic Areas:Oncology
Age Range:18 - Any
Start Date:January 14, 2015
End Date:January 2019
Contact:Jonathan Buscaglia, MD

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EUS-guided Biopsy of Pancreatic Mass Lesions for Developing Patient -Derived Cancer Models

Pancreatic cancer is a very aggressive cancer. Over the past 40 years there has not been much
progress made in reducing deaths from this cancer. Recently, new models of pancreatic cancers
have been generated from mouse and human tissues. These models have used larger pieces of
tissues taken from surgical removal of pancreatic cancers.

The purpose of this study is to determine whether these new pancreatic cancer models can be
generated from the small biopsies we take to make the diagnosis of the pancreatic mass.

The Endoscopic Ultrasound guided pancreatic biopsy tissue collected for only research
purposes will be used to generate organoids in a in-vivo and in-vitro setting.

The development of these methods may help scientists identify new treatments for pancreatic
cancer and to potentially develop more personalized approaches to treating pancreatic cancer.

Inclusion Criteria:

- Patients who are scheduled for an EUS-FNB performed by a member of the Stony Brook
Interventional Endoscopy Section of the Division of Gastroenterology and Hepatology

Exclusion Criteria:

- less than 18 years of age
We found this trial at
Stony Brook, New York 11794
Phone: 631-444-7225
Stony Brook, NY
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