Muscle Elastography in Spastic Cerebral Palsy
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Neurology, Neurology, Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 5 - 18 |
| Updated: | 5/27/2018 |
| Start Date: | December 14, 2017 |
| End Date: | April 2019 |
Use of Elastography to Quantify Change in Upper Extremity Muscle Spasticity Following Botox Injection in Children With Spastic Cerebral Palsy
To date, clinical tests are unable to differentiate between the cause of muscle stiffness,
although a manual instrumented spasticity assessment for the lower limb that utilizes surface
electromyogram has recently been proposed. This study intends to use shear wave elastography
to assess individual muscle stiffness parameters and the individual response to botulinum
toxin injection in the elbow and wrist flexors. Collection of baseline spasticity parameters
could then be used to predict the effect of botulinum toxin type A and ultimately serve as a
basis for development of a treatment model for muscle spasticity in patients with spastic
cerebral palsy.
although a manual instrumented spasticity assessment for the lower limb that utilizes surface
electromyogram has recently been proposed. This study intends to use shear wave elastography
to assess individual muscle stiffness parameters and the individual response to botulinum
toxin injection in the elbow and wrist flexors. Collection of baseline spasticity parameters
could then be used to predict the effect of botulinum toxin type A and ultimately serve as a
basis for development of a treatment model for muscle spasticity in patients with spastic
cerebral palsy.
Inclusion Criteria:
- Patients with unilateral spastic cerebral palsy with presence of dynamic muscle
spasticity in the elbow and/or wrist flexors, who will be able to provide consent.
- Consent may be obtained from a parent or legal guardian, as applicable.
Exclusion Criteria:
- Prior surgical procedure in the affected upper extremity
- Unrelated orthopedic injury to the affected upper extremity
- Current oral or intrathecal antispasticity therapy
- Prior Botulinum toxin type A injection in preceding 6 months
We found this trial at
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Hospital for Special Surgery Founded in 1863, Hospital for Special Surgery is the nation
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