Noninvasive Estimation of Work of Breathing



Status:Recruiting
Conditions:Hospital, Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases, Other
Healthy:No
Age Range:18 - Any
Updated:4/15/2017
Start Date:September 2016
End Date:December 2019
Contact:David H Chong, MD
Email:dhc5@cumc.columbia.edu
Phone:646-317-4777

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This study will evaluate the correlation between invasively measured parameters (work of
breathing/power of breathing, resistance and elastance), derived using esophageal pressure
measurements, and their corresponding non-invasive estimated values (noninvasive work of
breathing/power of breathing, resistance and elastance), computed using airway pressure and
flow measurements only.

This study will evaluate the correlation between invasively measured parameters (work of
breathing/power of breathing, resistance and elastance), derived using esophageal pressure
measurements, and their corresponding non-invasive estimated values (noninvasive work of
breathing/power of breathing, resistance and elastance), computed using airway pressure and
flow measurements only. Vent settings will be adjusted to test accuracy over a range of
respiratory support conditions.

Inclusion Criteria:

- Adult medical/surgical ICU patients (Age≥18) on mechanical ventilation for
respiratory failure, spontaneously breathing and receiving eligible for pressure
support ventilation (PSV).

Exclusion Criteria:

- Prisoners and patients with closed-head injury (e.g., trauma), hemodynamic
instability, multiple organ system failure or late term pregnancy will not be
studied.
We found this trial at
1
site
630 W 168th St
New York, New York
212-305-2862
Phone: 646-317-4777
Columbia University Medical Center Situated on a 20-acre campus in Northern Manhattan and accounting for...
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mi
from
New York, NY
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