Adaptive Radiotherapy for Head and Neck Cancer



Status:Recruiting
Conditions:Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:3/15/2019
Start Date:March 15, 2017
End Date:March 15, 2020
Contact:C. Jillian Tsai, MD
Email:tsaic@mskcc.org
Phone:631-623-4268

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A Prospective Non-Inferiority Trial of the Use of Adaptive Radiotherapy for Head and Neck Cancer Undergoing Radiation Therapy

The purpose of this study is to demonstrate that adaptive radiotherapy (ART) in head and neck
cancer patients are comparable to historical controls in head and neck patients undergoing
standard intensity-modulated radiation therapy (IMRT) without ART.


Inclusion Criteria:

- Participants with pathologically confirmed cancers of paranasal sinuses, oropharynx,
oral cavity, nasopharynx, larynx, hypopharynx, and unknown primary and will receive
definitive radiation therapy with or without chemotherapy.

- Karnofsky performance status >= 70%

- Women of childbearing potential need to have a negative serum pregnancy test at the
time of therapy

- Participants must have the ability to understand and the willingness to sign a written
consent form

Exclusion Criteria:

- Female participants who are pregnant or breast feeding

- Participants who are not able to comply with study and/or follow up procedures

- Participants who have received induction chemotherapy before radiation treatment

- Participants who had prior head and neck radiation therapy

- Participants who are enrolled in a national/international cooperative group trials

- Patients with metastatic disease
We found this trial at
8
sites
225 Summit Avenue
Montvale, New Jersey 07645
Phone: 631-623-4268
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Basking Ridge, New Jersey 07920
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Commack, New York 11725
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Harrison, New York
Phone: 631-623-4268
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Middletown, New Jersey 07748
Phone: 631-623-4268
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1275 York Ave
New York, New York 10021
(212) 639-2000
Phone: 631-623-4268
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Rockville Centre, New York 11570
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Uniondale, New York 11553
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Uniondale, NY
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