COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis



Status:Completed
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:10/14/2017
Start Date:June 2005
End Date:September 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase III, 12-Week, Multicentre, Double-Blind, Randomised, Placebo- and Active Comparator-Controlled, Parallel Group Study to Investigate the Efficacy and Safety of GW406381, 5mg, 10mg, 25mg, and 50mg Administered Orally Once Daily, in Adults With Rheumatoid Arthritis

This study is being conducted to find out if an investigational drug called GW406381 can help
people with rheumatoid arthritis.


Inclusion criteria:

- Rheumatoid arthritis (RA) for at least 12 months.

- Required a non-steroidal anti-inflammatory drug (NSAID) or COX-2 inhibitor for RA for
at least 5 out of 7 days of each week for the 4 weeks prior to screening.

Exclusion criteria:

- Any history of cardiovascular disease (e.g., heart attack, stroke, congestive heart
failure, uncontrolled high blood pressure), documented peripheral arterial
insufficiency and symptomatic, clinically significant claudication, or who have a
history of peripheral arterial embolism.

- Have an active stomach ulcer or history of any stomach tear or bleeding.
We found this trial at
89
sites
GSK Investigational Site
Anaheim, California 92807
1148
mi
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Anaheim, CA
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Anniston, Alabama 36207
728
mi
from
Anniston, AL
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GSK Investigational Site
Atlanta, Georgia 30341
801
mi
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Atlanta, GA
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GSK Investigational Site
Austin, Texas 78705
515
mi
from
Austin, TX
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GSK Investigational Site
Aventura, Florida 33180
1315
mi
from
Aventura, FL
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GSK Investigational Site
Berlin, New Jersey 08009
1237
mi
from
Berlin, NJ
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GSK Investigational Site
Birmingham, Alabama 35249
676
mi
from
Birmingham, AL
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GSK Investigational Site
Bridgeport, Connecticut 06606
1329
mi
from
Bridgeport, CT
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GSK Investigational Site
Charleston, South Carolina 29425
1063
mi
from
Charleston, SC
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GSK Investigational Site
Charlotte, North Carolina 28203
957
mi
from
Charlotte, NC
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GSK Investigational Site
Cleveland, Ohio 44195
898
mi
from
Cleveland, OH
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GSK Investigational Site
Colorado Springs, Colorado 80910
383
mi
from
Colorado Springs, CO
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GSK Investigational Site
Columbus, Ohio 43219
815
mi
from
Columbus, OH
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GSK Investigational Site
Concinnati, Ohio 45219
?
mi
from
Concinnati, OH
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GSK Investigational Site
Cordoba, Córdova
?
mi
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Cordoba,
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GSK Investigational Site
Dallas, Texas 75230
340
mi
from
Dallas, TX
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GSK Investigational Site
Danbury, Connecticut 06810
1317
mi
from
Danbury, CT
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GSK Investigational Site
Daytona Beach, Florida 32117
1127
mi
from
Daytona Beach, FL
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GSK Investigational Site
DeLand, Florida 32720
1124
mi
from
DeLand, FL
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GSK Investigational Site
Dover, New Hampshire 03820
1458
mi
from
Dover, NH
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GSK Investigational Site
Duncansville, Pennsylvania 16635
1053
mi
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Duncansville, PA
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GSK Investigational Site
Dunedin, Florida 34698
1099
mi
from
Dunedin, FL
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GSK Investigational Site
Evanston, Illinois 60201
613
mi
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Evanston, IL
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GSK Investigational Site
Evansville, Indiana 47714
561
mi
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Evansville, IN
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GSK Investigational Site
Everett, Washington 98201
1413
mi
from
Everett, WA
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GSK Investigational Site
Fall River, Massachusetts 02720
1439
mi
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Fall River, MA
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GSK Investigational Site
Gainsville, Georgia 30501
?
mi
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Gainsville, GA
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GSK Investigational Site
Gastonia, North Carolina 28054
940
mi
from
Gastonia, NC
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GSK Investigational Site
Glendale, Arizona 85304
854
mi
from
Glendale, AZ
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GSK Investigational Site
Greer, South Carolina 29651
888
mi
from
Greer, SC
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GSK Investigational Site
Hamden, Connecticut 06518
1345
mi
from
Hamden, CT
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GSK Investigational Site
Hampton, South Carolina 29924
997
mi
from
Hampton, SC
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GSK Investigational Site
Hickory, North Carolina 28601
921
mi
from
Hickory, NC
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GSK Investigational Site
Huntsville, Alabama 35801
661
mi
from
Huntsville, AL
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GSK Investigational Site
Idaho Falls, Idaho 83404
841
mi
from
Idaho Falls, ID
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GSK Investigational Site
Indianapolis, Indiana 46202
643
mi
from
Indianapolis, IN
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GSK Investigational Site
Johnson City, New York 13790
1193
mi
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Johnson City, NY
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GSK Investigational Site
Kalamazoo, Michigan 49007
718
mi
from
Kalamazoo, MI
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GSK Investigational Site
Kingston, New York 12401
1291
mi
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Kingston, NY
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GSK Investigational Site
Lansing, Michigan 48917
774
mi
from
Lansing, MI
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GSK Investigational Site
Largo, Florida 33770
1103
mi
from
Largo, FL
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GSK Investigational Site
Las Vegas, Nevada 89102
963
mi
from
Las Vegas, NV
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GSK Investigational Site
Louisville, Kentucky 40202
657
mi
from
Louisville, KY
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GSK Investigational Site
Mayfield Village, Ohio 44143
?
mi
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Mayfield Village, OH
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GSK Investigational Site
Medford, Oregon 97504
1357
mi
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Medford, OR
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GSK Investigational Site
Memphis, Tennessee 38120
478
mi
from
Memphis, TN
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GSK Investigational Site
Mercerville, New Jersey 08619
1250
mi
from
Mercerville, NJ
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GSK Investigational Site
Miami, Florida 33136
1320
mi
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Miami, FL
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GSK Investigational Site
Montgomery, Alabama 36109
751
mi
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Montgomery, AL
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GSK Investigational Site
Morton Grove, Illinois 60053
608
mi
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Morton Grove, IL
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GSK Investigational Site
Murrells Inlet, South Carolina 29576
1091
mi
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Murrells Inlet, SC
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GSK Investigational Site
New Orleans, Louisiana 70112
697
mi
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New Orleans, LA
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GSK Investigational Site
New York, New York 10032
1290
mi
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New York, NY
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GSK Investigational Site
North Massapequa, New York 11758
1315
mi
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North Massapequa, NY
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GSK Investigational Site
Ocala, Florida 34471
1080
mi
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Ocala, FL
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GSK Investigational Site
Oklahoma City, Oklahoma 73112
155
mi
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Oklahoma City, OK
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GSK Investigational Site
Orlando, Florida 32806
1144
mi
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Orlando, FL
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GSK Investigational Site
Palm Desert, California 92260
1077
mi
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Palm Desert, CA
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GSK Investigational Site
Palm Harbor, Florida 34684
1099
mi
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Palm Harbor, FL
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GSK Investigational Site
Philadelphia, Pennsylvania 19104
1223
mi
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Philadelphia, PA
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GSK Investigational Site
Port Orange, Florida 32129
1133
mi
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Port Orange, FL
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GSK Investigational Site
Prairie Village, Kansas 66208
193
mi
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Prairie Village, KS
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GSK Investigational Site
Racine, Wisconsin 53404
630
mi
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Racine, WI
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GSK Investigational Site
Reno, Nevada 89502
1185
mi
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Reno, NV
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GSK Investigational Site
Rochester, New York 14642
1121
mi
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Rochester, NY
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GSK Investigational Site
Roswell, Georgia 30076
797
mi
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Roswell, GA
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GSK Investigational Site
San Antonio, Texas 78258
561
mi
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San Antonio, TX
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GSK Investigational Site
San Diego, California 92111
1139
mi
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San Diego, CA
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GSK Investigational Site
Santa Monica, California 90404
1181
mi
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Santa Monica, CA
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GSK Investigational Site
Scottsdale, Arizona 85259
834
mi
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Scottsdale, AZ
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GSK Investigational Site
Slidell, Louisiana 70458
691
mi
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Slidell, LA
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GSK Investigational Site
Springfield, Illinois 62702
464
mi
from
Springfield, IL
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GSK Investigational Site
Springfield, Massachusetts 01199
1364
mi
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Springfield, MA
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GSK Investigational Site
St. Louis, Missouri 63110
415
mi
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St. Louis, MO
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GSK Investigational Site
Statesville, North Carolina 28625
945
mi
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Statesville, NC
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GSK Investigational Site
Stuart, Florida 34994
1253
mi
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Stuart, FL
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GSK Investigational Site
Tampa, Florida 33612
1112
mi
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Tampa, FL
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GSK Investigational Site
Trinity, Florida 34655
1096
mi
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Trinity, FL
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GSK Investigational Site
Trumbull, Connecticut 06611
1329
mi
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Trumbull, CT
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GSK Investigational Site
Tucson, Arizona 85724
833
mi
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Tucson, AZ
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GSK Investigational Site
Tulsa, Oklahoma 74105
152
mi
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Tulsa, OK
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GSK Investigational Site
Upland, California 91786
1135
mi
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Upland, CA
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GSK Investigational Site
Vancouver, Washington 98684
1378
mi
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Vancouver, WA
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GSK Investigational Site
West Palm Beach, Florida 33409
1282
mi
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West Palm Beach, FL
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GSK Investigational Site
West Reading, Pennsylvania 19611
1184
mi
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West Reading, PA
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GSK Investigational Site
Wheaton, Maryland 20902
1125
mi
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Wheaton, MD
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GSK Investigational Site
Wichita, Kansas 67207
32
mi
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Wichita, KS
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GSK Investigational Site
Woodstock, Georgia 30189
784
mi
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Woodstock, GA
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GSK Investigational Site
Zephyrhills, Florida 33540
1117
mi
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Zephyrhills, FL
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