Administration of Kisspeptin in Patients With Hyperprolactinemia
| Status: | Recruiting |
|---|---|
| Conditions: | Endocrine |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 12/27/2018 |
| Start Date: | September 22, 2017 |
| End Date: | February 2021 |
| Contact: | Isabella McDonald |
| Email: | mghkisspeptinresearch@partners.org |
| Phone: | 617-726-8484 |
The goal of this project is to explore the use of exogenous pulsatile kisspeptin as a
therapeutic alternative for patients with hyperprolactinemia who are intolerant to current
therapies.
Funding Source - FDA OOPD
therapeutic alternative for patients with hyperprolactinemia who are intolerant to current
therapies.
Funding Source - FDA OOPD
Inclusion/Exclusion Criteria:
- confirmed diagnosis of elevated levels of prolactin measured via blood test,
- no pituitary adenoma or a microprolactinoma (<10 mm). Patients with a
macroprolactinoma confirmed on MRI imaging will be excluded,
- no history of a medication reaction requiring emergency medical care,
- no illicit drug use or excessive alcohol consumption (<10 drinks/week),
- not currently seeking fertility, breastfeeding or pregnant,
- no history of bilateral oophorectomy,
- willing to complete a dopamine agonist washout,
- normal physical exam and laboratory studies within reference range.
We found this trial at
1
site
185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Phone: 617-726-8484
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