Evaluation of Liquid vs. Tablet Buprenorphine - 6



Status:Completed
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:21 - 50
Updated:1/13/2017
Start Date:August 1996
End Date:August 2000

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Trial Summary
Trial Overview
Inclusion Criteria

Pharmacokinetics and Bioavailability of Liquid vs Tablet Buprenorphine

The purpose of this study is to evaluate the steady-state pharmacokinetics and
bioavailability of buprenorphine sublingual tablets vs. sublingual solution.


Inclusion Criteria:

M/F ages 21-50. Meet DSM-IV criteria for opioid dependence. Agree to conditions of the
study and sign informed consent.

Exclusion Criteria:

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant
and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics.
Acute hepatitis. Other medical condtions that deem participation to be unsafe.
We found this trial at
1
site
Friends Research Institute
Los Angeles, California 90025
?
mi
from
Los Angeles, CA
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