Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)



Status:Recruiting
Conditions:Hematology
Therapuetic Areas:Hematology
Healthy:No
Age Range:18 - Any
Updated:2/8/2019
Start Date:December 2016
End Date:March 2022
Contact:MOST Study (Incyte Corporation)
Email:IncyteMFandETStudy@syneoshealth.com

Use our guide to learn which trials are right for you!

Prospective, Longitudinal, Non-Interventional Study of Disease Burden and Treatment of Patients With Low-Risk Myelofibrosis (MF) or High-Risk Essential Thrombocythemia (ET) or ET Patients Receiving ET-Directed Therapy

The purpose of this prospective, longitudinal, noninterventional study is to describe
clinical characteristics, evolution of disease burden, and treatment patterns in patients
with select subcategories of essential thrombocythemia (ET) or myelofibrosis (MF).


Inclusion Criteria:

- MF cohort: Diagnosis of MF and low-risk using DIPSS risk categorization OR
intermediate-1 risk by DIPSS by reason of age alone.

- ET cohort: Diagnosis of ET and age ≥ 60 years OR history of thromboembolic events OR
currently receiving ET-directed therapy (eg, hydroxyurea, anagrelide, interferon,
busulfan, ruxolitinib, etc).

- Willing and able to provide written informed consent.

- Willing and able to complete patient assessment questionnaires either alone or with
minimal assistance from a caregiver and/or trained site personnel.

- Under the supervision of a physician for the current care of MF or ET.

Exclusion Criteria:

- Individuals who are participating in blinded investigational drug studies.

- Individuals who are participating in Incyte investigational/interventional drug trials
(company- or investigator-sponsored studies) until they have completed the 30-day end
of study visit.

- Life expectancy ≤ 6 months.

- Diagnosis of secondary acute myeloid leukemia, myelodysplastic syndrome, chronic
myelogenous leukemia, or secondary thrombocytosis.
We found this trial at
115
sites
1463
mi
from 91732
Little Rock, AR
Click here to add this to my saved trials
2437
mi
from 91732
Albany, NY
Click here to add this to my saved trials
1494
mi
from 91732
Alexandria, LA
Click here to add this to my saved trials
922
mi
from 91732
Amarillo, TX
Click here to add this to my saved trials
1430
mi
from 91732
Ames, IA
Click here to add this to my saved trials
1819
mi
from 91732
Anderson, IN
Click here to add this to my saved trials
1204
mi
from 91732
Arlington, TX
Click here to add this to my saved trials
825
mi
from 91732
Aurora, CO
Click here to add this to my saved trials
2319
mi
from 91732
Aventura, FL
Click here to add this to my saved trials
1780
mi
from 91732
Avon, IN
Click here to add this to my saved trials
2301
mi
from 91732
Baltimore, MD
Click here to add this to my saved trials
?
mi
from 91732
Bayamon,
Click here to add this to my saved trials
1423
mi
from 91732
Beaumont, TX
Click here to add this to my saved trials
354
mi
from 91732
Berkeley, CA
Click here to add this to my saved trials
2277
mi
from 91732
Bethesda, MD
Click here to add this to my saved trials
2361
mi
from 91732
Bethlehem, PA
Click here to add this to my saved trials
951
mi
from 91732
Billings, MT
Click here to add this to my saved trials
665
mi
from 91732
Boise, ID
Click here to add this to my saved trials
1395
mi
from 91732
Bolivar, MO
Click here to add this to my saved trials
2046
mi
from 91732
Boone, NC
Click here to add this to my saved trials
2578
mi
from 91732
Boston, MA
Click here to add this to my saved trials
2309
mi
from 91732
Boynton Beach, FL
Click here to add this to my saved trials
2430
mi
from 91732
Brick, NJ
Click here to add this to my saved trials
2016
mi
from 91732
Bristol, VA
Click here to add this to my saved trials
2434
mi
from 91732
Brooklyn, NY
Click here to add this to my saved trials
1282
mi
from 91732
Bryan, TX
Click here to add this to my saved trials
2044
mi
from 91732
Canton, OH
Click here to add this to my saved trials
1606
mi
from 91732
Cape Girardeau, MO
Click here to add this to my saved trials
Charlotte, North Carolina 28207
2102
mi
from 91732
Charlotte, NC
Click here to add this to my saved trials
1729
mi
from 91732
Chicago, IL
Click here to add this to my saved trials
1880
mi
from 91732
Cincinnati, OH
Click here to add this to my saved trials
2032
mi
from 91732
Cleveland, OH
Click here to add this to my saved trials
Colorado Springs, Colorado 80910
804
mi
from 91732
Colorado Springs, CO
Click here to add this to my saved trials
2288
mi
from 91732
Columbia, MD
Click here to add this to my saved trials
1902
mi
from 91732
Columbus, GA
Click here to add this to my saved trials
1644
mi
from 91732
Covington, LA
Click here to add this to my saved trials
1225
mi
from 91732
Dallas, TX
Click here to add this to my saved trials
1867
mi
from 91732
Danville, KY
Click here to add this to my saved trials
2295
mi
from 91732
Danville, PA
Click here to add this to my saved trials
2347
mi
from 91732
Dunmore, PA
Click here to add this to my saved trials
2202
mi
from 91732
Durham, NC
Click here to add this to my saved trials
2421
mi
from 91732
East Orange, NJ
Click here to add this to my saved trials
2479
mi
from 91732
East Setauket, NY
Click here to add this to my saved trials
Elk Grove Village, Illinois 60007
1711
mi
from 91732
Elk Grove Village, IL
Click here to add this to my saved trials
2284
mi
from 91732
Elmira, NY
Click here to add this to my saved trials
2412
mi
from 91732
Florham Park, NJ
Click here to add this to my saved trials
840
mi
from 91732
Fort Collins, CO
Click here to add this to my saved trials
2315
mi
from 91732
Fort Lauderdale, FL
Click here to add this to my saved trials
2266
mi
from 91732
Gettysburg, PA
Click here to add this to my saved trials
1174
mi
from 91732
Grand Island, NE
Click here to add this to my saved trials
Greenville, North Carolina 27834
2290
mi
from 91732
Greenville, NC
Click here to add this to my saved trials
1725
mi
from 91732
Harvey, IL
Click here to add this to my saved trials
Hendersonville, North Carolina 28791
2010
mi
from 91732
Hendersonville, NC
Click here to add this to my saved trials
45
mi
from 91732
Highland, CA
Click here to add this to my saved trials
1357
mi
from 91732
Houston, TX
Click here to add this to my saved trials
1785
mi
from 91732
Huntsville, AL
Click here to add this to my saved trials
1793
mi
from 91732
Indianapolis, IN
Click here to add this to my saved trials
?
mi
from 91732
Jackson, MN
Click here to add this to my saved trials
1653
mi
from 91732
Jackson, TN
Click here to add this to my saved trials
2127
mi
from 91732
Jacksonville, FL
Click here to add this to my saved trials
1462
mi
from 91732
Jefferson City, MO
Click here to add this to my saved trials
994
mi
from 91732
Kalispell, MT
Click here to add this to my saved trials
Lancaster, South Carolina 29720
2111
mi
from 91732
Lancaster, SC
Click here to add this to my saved trials
1894
mi
from 91732
Lansing, MI
Click here to add this to my saved trials
?
mi
from 91732
Lansing, MN
Click here to add this to my saved trials
208
mi
from 91732
Las Vegas, NV
Click here to add this to my saved trials
2515
mi
from 91732
Lebanon, NH
Click here to add this to my saved trials
21
mi
from 91732
Long Beach, CA
Click here to add this to my saved trials
1908
mi
from 91732
Marietta, GA
Click here to add this to my saved trials
1655
mi
from 91732
Marrero, LA
Click here to add this to my saved trials
2229
mi
from 91732
Martinsburg, WV
Click here to add this to my saved trials
1718
mi
from 91732
Maywood, IL
Click here to add this to my saved trials
1297
mi
from 91732
McAllen, TX
Click here to add this to my saved trials
1232
mi
from 91732
McKinney, TX
Click here to add this to my saved trials
1235
mi
from 91732
Mesquite, TX
Click here to add this to my saved trials
2499
mi
from 91732
Middletown, CT
Click here to add this to my saved trials
932
mi
from 91732
Midland, TX
Click here to add this to my saved trials
1722
mi
from 91732
Milwaukee, WI
Click here to add this to my saved trials
2407
mi
from 91732
Morristown, NJ
Click here to add this to my saved trials
1911
mi
from 91732
Mount Sterling, KY
Click here to add this to my saved trials
2435
mi
from 91732
New York, NY
Click here to add this to my saved trials
1648
mi
from 91732
Normal, IL
Click here to add this to my saved trials
73
mi
from 91732
Oceanside, CA
Click here to add this to my saved trials
1300
mi
from 91732
Omaha, NE
Click here to add this to my saved trials
1659
mi
from 91732
Paducah, KY
Click here to add this to my saved trials
329
mi
from 91732
Palo Alto, CA
Click here to add this to my saved trials
2428
mi
from 91732
Paramus, NJ
Click here to add this to my saved trials
2306
mi
from 91732
Pembroke Pines, FL
Click here to add this to my saved trials
2119
mi
from 91732
Pittsburgh, PA
Click here to add this to my saved trials
1720
mi
from 91732
River Forest, IL
Click here to add this to my saved trials
2245
mi
from 91732
Rochester, NY
Click here to add this to my saved trials
2671
mi
from 91732
Rockport, ME
Click here to add this to my saved trials
1573
mi
from 91732
Saint Louis, MO
Click here to add this to my saved trials
1188
mi
from 91732
San Antonio, TX
Click here to add this to my saved trials
397
mi
from 91732
Santa Rosa, CA
Click here to add this to my saved trials
964
mi
from 91732
Seattle, WA
Click here to add this to my saved trials
1724
mi
from 91732
Skokie, IL
Click here to add this to my saved trials
Spartanburg, South Carolina 29303
2042
mi
from 91732
Spartanburg, SC
Click here to add this to my saved trials
2428
mi
from 91732
Staten Island, NY
Click here to add this to my saved trials
2136
mi
from 91732
Tampa, FL
Click here to add this to my saved trials
353
mi
from 91732
Tempe, AZ
Click here to add this to my saved trials