Screening in Oculopharyngeal Muscular Dystrophy
| Status: | Recruiting |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 6/27/2018 |
| Start Date: | October 2016 |
| End Date: | June 2019 |
| Contact: | Kelby Magennis, MPH |
| Email: | kmagennis@phhp.ufl.edu |
| Phone: | 352-273-8632 |
Determination of Accurate Screening Tools for Dysphagia in Oculopharyngeal Muscular Dystrophy
Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathic disease that results in
progressive degeneration of the oral and pharyngeal muscular, resulting in severe dysphagia
and dysarthria. OPMD is considered a rare disease; therefore, limited research is available
on the natural progression of the disease or the utility of biomarkers to identify swallowing
impairment. The aim of this study is:
1. To identify accurate, reliable and non-invasive clinical markers of swallowing
impairment
2. To determine the discriminate ability of these markers to identify impairments in
swallow safety and swallowing efficiency.
progressive degeneration of the oral and pharyngeal muscular, resulting in severe dysphagia
and dysarthria. OPMD is considered a rare disease; therefore, limited research is available
on the natural progression of the disease or the utility of biomarkers to identify swallowing
impairment. The aim of this study is:
1. To identify accurate, reliable and non-invasive clinical markers of swallowing
impairment
2. To determine the discriminate ability of these markers to identify impairments in
swallow safety and swallowing efficiency.
Participants will be recruited from the Neurology clinic at the University of Florida. The
single evaluation will occur in the PIs research laboratory at the University of Florida,
Gainesville, Florida.
single evaluation will occur in the PIs research laboratory at the University of Florida,
Gainesville, Florida.
Inclusion Criteria:
- diagnosis of oculopharyngeal muscular dystrophy
- no allergies to barium or capsaicin,
- no tracheotomy or mechanical ventilation
- no significant concurrent respiratory disease (e.g., COPD).
Exclusion Criteria:
- Pregnant Women
We found this trial at
1
site
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
Click here to add this to my saved trials
