Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis



Status:Recruiting
Conditions:Colitis, Colitis, Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 75
Updated:3/22/2019
Start Date:February 3, 2017
End Date:June 19, 2021
Contact:Pfizer CT.gov Call Center
Email:ClinicalTrials.gov_Inquiries@pfizer.com
Phone:1-800-718-1021

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A PHASE 2B, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PARALLEL GROUP, DOSE RANGING STUDY OF ORAL PF-06651600 AND PF-06700841 AS INDUCTION AND CHRONIC THERAPY IN SUBJECTS WITH MODERATE TO SEVERE ULCERATIVE COLITIS

The purpose of this study is to determine whether PF-06651600 and PF-06700841 are effective
in treatment of moderate to severe ulcerative colitis.


Inclusion Criteria:

- Diagnosis of ulcerative colitis for greater than/equal to 3 months.

- Moderate to severe active ulcerative colitis

- Inadequate response to, loss of response to, or intolerance to at least one
conventional therapy for UC.

Exclusion Criteria:

- Pregnant or breastfeeding

- Clinical findings suggestive of Crohn's Disease

- History of bowel surgery within 6 months
We found this trial at
80
sites
2201 Inwood Rd
Dallas, Texas 75235
(214) 645-8300
U.T. Southwestern Medical Center The story of UT Southwestern Medical Center is one of commitment...
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75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
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Bronx, NY
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Chapel Hill, North Carolina 27599
(919) 962-2211
University of North Carolina at Chapel Hill Carolina’s vibrant people and programs attest to the...
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300 Community Drive
Manhasset, New York 11030
(516) 562-0100
North Shore University Hospital North Shore-LIJ Health System includes 16 award-winning hospitals and nearly 400...
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Manhasset, NY
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1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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601 Elmwood Avenue
Rochester, New York 14642
(585) 275-2100
Univ of Rochester Medical Center One of the nation's top academic medical centers, the University...
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Rochester, NY
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Seattle, Washington 98104
(206) 543-2100
Univ of Washington Founded in 1861 by a private gift of 10 acres in what...
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Arlington Heights, Illinois 60005
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9675 Brighton Way # B1
Beverly Hills, California 90210
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Bristol, Connecticut 06010
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39 Brewster Road
Bristol, Connecticut 06010
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Chapel Hill, North Carolina 27514
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Chapel Hill, North Carolina 27599
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Chapel Hill, North Carolina 27517
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Chestnut Hill, Massachusetts 02467
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Chevy Chase, Maryland 20815
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5454 Wisconsin Avenue
Chevy Chase, Maryland 20815
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Clearwater, Florida 33762
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Clearwater, Florida 33756
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7120 Minstrel Way
Columbia, Maryland 21045
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Columbia, Maryland 21045
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5323 Harry Hines Boulevard
Dallas, Texas 75390
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480 Honeysuckle Road
Dothan, Alabama 36305
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Dothan, Alabama 36301
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Fairfax, Virginia 22031
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Germantown, Tennessee 38138
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865 Northern Boulevard
Great Neck, New York 11021
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Houma, Louisiana 70360
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Houma, Louisiana 70360
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Houston, Texas 77004
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180 Bear Creek Parkway
Keller, Texas 76248
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La Jolla, California 92037
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La Jolla, California 92037
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La Jolla, California 92037
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2008 Pacific Avenue
Long Beach, California 90806
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Los Angeles, California 90067
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Los Angeles, California 90036
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1400 NW 12th Ave
Miami, Florida 33136
(305) 689-5511
University of Miami Hospital The University of Miami changed the face of modern health care...
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550 1st Ave
New York, New York 10016
(212) 263-7300
New York University Langone Medical Center NYU NYU Langone Medical Center, a world-class, patient-centered, integrated,...
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New York, New York 10016
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New York, New York 10016
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540 1st Avenue
New York, New York 10016
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New York, New York 10016
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535 2nd Avenue
New York, New York 10016
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New York, New York 10021
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Oak Lawn, Illinois 60453
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4901 Vineland Road
Orlando, Florida 32811
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Orlando, Florida 32819
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Orlando, Florida 32835
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Palos Heights, Illinois 60463
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Plainville, Connecticut 06062
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1201 Broad Rock Boulevard
Richmond, Virginia 23249
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Rockville, Maryland 20850
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San Antonio, Texas 78229
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San Diego, California 92103
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San Diego, California 92103
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San Diego, California 92123
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505 Nolen Drive
Southlake, Texas 76092
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Tomball, Texas 77375
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Worcester, Massachusetts 01605
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55 N Lake Ave
Worcester, Massachusetts 01655
(508) 856-8989
Univ of Massachusetts Med School As the commonwealth's only public medical school, we take seriously...
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