Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery



Status:Recruiting
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/6/2019
Start Date:October 20, 2016

Use our guide to learn which trials are right for you!

A Phase II and Pilot Trial of PD-1 Blockade With MK-3475 (Pembrolizumab) in Patients With Resectable or Unresectable Desmoplastic Melanoma (DM)

This pilot phase II trial studies how well pembrolizumab works in treating patients with
desmoplastic melanoma (DM) that can or cannot be removed by surgery. Monoclonal antibodies,
like pembrolizumab, may block specific proteins which may strengthen the immune system and
control tumor growth.

PRIMARY OBJECTIVES:

I. To evaluate the pathologic complete response rate (pCR) in patients with resectable
desmoplastic melanoma treated with neoadjuvant MK-3475 (pembrolizumab). (Cohort A) II. To
evaluate the complete response rate (confirmed and unconfirmed) in patients with unresectable
desmoplastic melanoma treated with MK-3475 (pembrolizumab). (Cohort B)

SECONDARY OBJECTIVES:

I. To estimate the 9 week response rate (RR) (unconfirmed complete and partial responses)
among patients with measurable disease. (Cohort A) II. To estimate the median overall
survival (OS). (Cohort A) III. To evaluate safety and tolerability of MK-3475 (pembrolizumab)
in the neoadjuvant setting. (Cohort A) IV. To estimate the median progression-free survival
(PFS). (Cohort B) V. To estimate the median overall survival (OS). (Cohort B) VI. To evaluate
safety and tolerability of MK-3475 (pembrolizumab) in this setting. (Cohort B)

TERTIARY OBJECTIVES:

I. To evaluate the hypothesis that higher mutational load in the patient derived baseline
tumor biopsy samples is associated with higher pathologic complete response (pCR).

II. To evaluate T cell infiltration into the tumors in DM patients and correlate with
response to programmed cell death protein 1 (PD-1) blockade.

III. To evaluate the clonality of tumor infiltrating T cells in DM patients and correlate
with response to PD-1 blockade.

IV. To evaluate adaptive immune resistant mechanism in DM tumors.

OUTLINE: Patients are assigned to 1 of 2 cohorts.

COHORT A: Patients receive pembrolizumab intravenously (IV) over 30 minutes on day 1.
Treatment repeats every 21 days for up to 3 courses. Patients with potentially resectable
disease undergo surgery. Patients with tumor progression and unresectable disease may receive
one additional course of pembrolizumab.

COHORT B: Patients with unresectable disease receive pembrolizumab IV over 30 minutes on day
1. Treatment repeats every 21 days for up to 34 courses in the absence of disease progression
or toxicity.

After completion of study treatment, patients are followed up at 6 and 12 weeks, then every 3
months for 1 year, and every 6 months for 4 years.

Inclusion Criteria:

- COHORT A: Patients must have histologically or cytologically confirmed primary
desmoplastic melanoma that is deemed resectable; the decision to perform surgery on
patients must be based on good clinical judgment; eligible patients for surgical
resection must have disease that, in the judgment of the surgeon, is deemed completely
resectable resulting in free surgical margins; patients must have residual disease
after initial biopsy which can be measurable or non-measurable disease per Response
Evaluation Criteria in Solid Tumors (RECIST) 1.1; residual disease can either be
confirmed with fine-needle aspiration (FNA) or if measurable disease is present, no
FNA needs to be obtained OR

- COHORT B: Patients must have histologically or cytologically confirmed primary
desmoplastic melanoma that is unresectable; patients in Cohort B must have measurable
disease per RECIST 1.1

- Contrast-enhanced computed tomography (CT) scans of the chest, abdomen and pelvis are
required; a whole body positron emission tomography (PET)/CT scan with diagnostic
quality images and intravenous iodinated contrast may be used in lieu of a contrast
enhanced CT of the chest, abdomen and pelvis; imaging of the head and neck is required
only if the patient has a head/neck primary; contrast may be omitted if the treating
investigator believes that exposure to contrast poses an excessive risk to the
patient; if skin lesions are being followed as measurable disease, photograph with a
ruler included and physician measurements, must be kept in the patient's chart as
source documentation; all measurable lesions must be assessed within 28 days prior to
registration; tests to assess non-measurable disease must be performed within 42 days
prior to registration; all disease must be assessed and documented on the baseline
tumor assessment form (RECIST 1.1)

- Patients must not have known brain metastases unless brain metastases have been
treated and patient is asymptomatic with no residual neurological dysfunction and has
not received enzyme-reducing anti-epileptic drugs or corticosteroids for at least 14
days prior to registration

- Patients must not have received prior systemic treatment for this melanoma

- Patients must not be planning to receive concomitant other biologic therapy, radiation
therapy, hormonal therapy, other chemotherapy, anti-cancer surgery or other
anti-cancer therapy while on this protocol

- Patients must not have received radiation therapy, non-cytotoxic agents or
investigational agents or systemic corticosteroids within 14 days prior to
registration

- Patients may have received prior surgery; all adverse events associated with prior
surgery must have resolved to =< grade 1 (per Common Terminology Criteria for Adverse
Events [CTCAE] 4.0) prior to registration

- Obtained within 28 days prior to registration: Absolute neutrophil count (ANC) >=
1,500/mcl

- Obtained within 28 days prior to registration: Platelets >= 50,000/mcl

- Obtained within 28 days prior to registration: Hemoglobin >= 8 g/dL

- Obtained within 28 days prior to registration: Total bilirubin =< 1.5 x institutional
upper limit of normal (IULN) (or =< 3.0 x IULN with Gilbert's syndrome)

- Obtained within 28 days prior to registration: Aspartate aminotransferase (AST) and
alanine aminotransferase (ALT) =< 2.5 x IULN (or < 5 x IULN for patients with known
liver metastases)

- Patients must have lactate dehydrogenase (LDH) performed within 28 days prior to
registration

- Patients must have Zubrod performance status =< 2

- Patients must not have history of (non-infectious) pneumonitis that required steroids
or current pneumonitis

- Patients must not have an active infection requiring systemic therapy

- Patients must not have active autoimmune disease that has required systemic treatment
in past 2 years (i.e., with use of disease modifying agents, corticosteroids or
immunosuppressive drugs); replacement therapy (e.g., thyroxine, insulin, or
physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency,
etc.) is not considered a form of systemic treatment

- Patients must not have received live vaccines within 42 days prior to registration;
examples of live vaccines include, but are not limited to, the following: measles,
mumps, rubella, chicken pox, shingles, yellow fever, rabies, Bacillus Calmette-Guerin
(BCG), and typhoid (oral) vaccine; seasonal influenza vaccines for injection are
allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are not allowed

- Patients known to be human immunodeficiency virus (HIV) positive are eligible if they
meet the following criteria within 30 days prior to registration: stable and adequate
CD4 counts (>= 350 mm^3), and serum HIV viral load of < 25,000 IU/ml; patients must be
on a stable anti-viral therapy

- No other prior malignancy is allowed except for the following: adequately treated
basal cell or squamous cell skin cancer, adequately treated in situ cancer, adequately
treated stage I or II cancer (including multiple primary melanomas) from which the
patient is currently in complete remission, or any other cancer from which the patient
has been disease free for three years

- Women of childbearing potential must have a negative urine or serum pregnancy test
within 28 days prior to registration; women/men of reproductive potential must have
agreed to use an effective contraceptive method for the course of the study through
120 days after the last dose of study medication; should a woman become pregnant or
suspect she is pregnant while she or her partner is participating in this study, she
should inform her treating physician immediately; a woman is considered to be of
"reproductive potential" if she has had menses at any time in the preceding 12
consecutive months; in addition to routine contraceptive methods, "effective
contraception" also includes heterosexual celibacy and surgery intended to prevent
pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy,
bilateral oophorectomy, or bilateral tubal ligation; however, if at any point a
previously celibate patient chooses to become heterosexually active during the time
period for use of contraceptive measures outlined in the protocol, he/she is
responsible for beginning contraceptive measures; patients must not be pregnant or
nursing

- Patients must have specimens available and institutions must be planning to submit for
centralized pathology review and for integrated translational medicine objectives

- Patients must be informed of the investigational nature of this study and must sign
and give written informed consent in accordance with institutional and federal
guidelines

- As a part of the Oncology Patient Enrollment Network (OPEN) registration process, the
treating institution's identity is provided in order to ensure that the current
(within 365 days) date of institutional review board approval for this study has been
entered in the system
We found this trial at
168
sites
3333 W Deyoung St
Saint Joseph, Missouri 64506
(618) 998-7000
Principal Investigator: Jay W. Carlson
Phone: 816-271-7937
Heartland Regional Medical Center Heartland Regional Medical Center is your community healthcare provider; a 98-bed...
?
mi
from
Saint Joseph, MO
Click here to add this to my saved trials
666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Principal Investigator: Marc S. Ernstoff
Phone: 800-767-9355
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
?
mi
from
Buffalo, NY
Click here to add this to my saved trials
1500 E Duarte Rd
Duarte, California 91010
(626) 256-4673
Principal Investigator: Kim A. Margolin
Phone: 800-826-4673
City of Hope Comprehensive Cancer Center City of Hope is a leading research and treatment...
?
mi
from
Duarte, CA
Click here to add this to my saved trials
4725 North Federal Highway
Fort Lauderdale, Florida 33308
(954) 771-8000
Principal Investigator: Jose Lutzky
Phone: 954-267-7750
Holy Cross Hospital While spirituality plays an essential role in the way that we minister...
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
170 North 1100 East
American Fork, Utah 84003
Principal Investigator: Tawnya L. Bowles
Phone: 801-855-4100
?
mi
from
American Fork, UT
Click here to add this to my saved trials
Anaconda, Montana 59711
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
?
mi
from
Anaconda, MT
Click here to add this to my saved trials
2000 Ogden Ave
Aurora, Illinois 60504
(630) 978-6200
Principal Investigator: James R. Egner
Phone: 630-978-6212
Rush - Copley Medical Center Rush-Copley is proud to be the leading provider of health...
?
mi
from
Aurora, IL
Click here to add this to my saved trials
Aventura, Florida 33180
Principal Investigator: Jose Lutzky
Phone: 305-674-2625
?
mi
from
Aventura, FL
Click here to add this to my saved trials
3325 Pocahontas Road
Baker City, Oregon 97814
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Baker City, OR
Click here to add this to my saved trials
Ballwin, Missouri 63011
Principal Investigator: Jay W. Carlson
Phone: 314-251-7058
?
mi
from
Ballwin, MO
Click here to add this to my saved trials
800 Farson Street
Belpre, Ohio 45714
(740) 401-0417
Principal Investigator: Timothy D. Moore
Phone: 800-523-3977
Strecker Cancer Center-Belpre The Memorial Health System's Strecker Cancer Center, Belpre combines the clinical expertise...
?
mi
from
Belpre, OH
Click here to add this to my saved trials
Billings, Montana 59101
Principal Investigator: Benjamin T. Marchello
Phone: 800-996-2663
?
mi
from
Billings, MT
Click here to add this to my saved trials
Boise, Idaho 83706
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Boise, ID
Click here to add this to my saved trials
Bolivar, Missouri 65613
Principal Investigator: Rakesh Gaur
Phone: 800-328-6010
?
mi
from
Bolivar, MO
Click here to add this to my saved trials
915 Highland Blvd
Bozeman, Montana 59715
(406) 414-5000
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Bozeman Deaconess Hospital Bozeman Deaconess Hospital is a Joint Commission certified, licensed Level III trauma...
?
mi
from
Bozeman, MT
Click here to add this to my saved trials
Branson, Missouri 65616
Principal Investigator: Jay W. Carlson
Phone: 417-269-4520
?
mi
from
Branson, MO
Click here to add this to my saved trials
201 E Nicollet Blvd
Burnsville, Minnesota 55337
(952) 892-2000
Principal Investigator: David M. King
Phone: 952-993-1517
Fairview Ridges Hospital Fairview Ridges Hospital is a 150-bed, Level III Trauma Care facility, offering...
?
mi
from
Burnsville, MN
Click here to add this to my saved trials
3123 Medical Dr
Caldwell, Idaho 83605
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Caldwell, ID
Click here to add this to my saved trials
1303 North Main Street
Cedar City, Utah 84721
(435) 868-5680
Principal Investigator: Tawnya L. Bowles
Phone: 435-868-5680
Sandra L. Maxwell Cancer Center The Huntsman-Intermountain Cancer Center at Valley View Medical Center in...
?
mi
from
Cedar City, UT
Click here to add this to my saved trials
303 East Superior Street
Chicago, Illinois 60611
Principal Investigator: Sunandana Chandra
Phone: 312-695-1301
?
mi
from
Chicago, IL
Click here to add this to my saved trials
272 Hospital Rd
Chillicothe, Ohio 45601
740-779-7500
Principal Investigator: Timothy D. Moore
Phone: 877-779-7585
Adena Regional Medical Center Since 1895, Adena Health System has remained focused on its commitment...
?
mi
from
Chillicothe, OH
Click here to add this to my saved trials
Clinton, North Carolina 28328
Principal Investigator: Nagesh H. Jayaram
Phone: 919-587-9077
?
mi
from
Clinton, NC
Click here to add this to my saved trials
Cody, Wyoming 82414
Principal Investigator: Benjamin T. Marchello
Phone: 800-996-2663
?
mi
from
Cody, WY
Click here to add this to my saved trials
Coeur d'Alene, Idaho 83814
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
?
mi
from
Coeur d'Alene, ID
Click here to add this to my saved trials
1400 West 4th Street
Coffeyville, Kansas 67337
Principal Investigator: Gary C. Doolittle
Phone: 620-252-1606
?
mi
from
Coffeyville, KS
Click here to add this to my saved trials
Columbus, Ohio 43210
Principal Investigator: Kari L. Kendra
Phone: 800-293-5066
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Columbus, Ohio 43213
Principal Investigator: Timothy D. Moore
Phone: 614-488-2118
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Columbus, Ohio 43222
Principal Investigator: Timothy D. Moore
Phone: 614-234-5433
?
mi
from
Columbus, OH
Click here to add this to my saved trials
5100 W Broad St
Columbus, Ohio 43228
(614) 544-1000
Principal Investigator: Timothy D. Moore
Phone: 614-566-3275
Doctors Hospital Nationally recognized for care quality and patient safety and satisfaction, Doctors Hospital is...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
810 Jasonway Avenue
Columbus, Ohio 43214
614/442-3130
Principal Investigator: Timothy D. Moore
Phone: 614-488-2118
Columbus Oncology and Hematology Associates Inc Columbus Oncology and Hematology Associates is a group of...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
3535 Olentangy River Rd
Columbus, Ohio 43214
(614) 566-5000
Principal Investigator: Timothy D. Moore
Phone: 614-566-4475
Riverside Methodist Hospital Serving central Ohio since 1892, Riverside Methodist Hospital is consistently ranked one...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
111 S Grant Ave
Columbus, Ohio 43215
(614) 566-9000
Principal Investigator: Timothy D. Moore
Phone: 614-566-4475
Grant Medical Center Founded in 1900 in Columbus' downtown, Grant has grown into one of...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
3100 Plaza Properties Blvd
Columbus, Ohio 43219
(614) 383-6000
Principal Investigator: Timothy D. Moore
Phone: 614-488-2118
The Mark H. Zangmeister Center At The Zangmeister Center, we appreciate that our patients have...
?
mi
from
Columbus, OH
Click here to add this to my saved trials
4050 Coon Rapids Blvd NW
Coon Rapids, Minnesota 55433
(763) 236-6000
Principal Investigator: David M. King
Phone: 952-993-1517
Mercy Hospital Mercy Hospital, located in Coon Rapids, Minnesota, is a 271-bed non-profit hospital that...
?
mi
from
Coon Rapids, MN
Click here to add this to my saved trials
Danville, Illinois 61832
Principal Investigator: James R. Egner
Phone: 800-446-5532
?
mi
from
Danville, IL
Click here to add this to my saved trials
Delaware, Ohio 43015
Principal Investigator: Timothy D. Moore
Phone: 614-488-2745
?
mi
from
Delaware, OH
Click here to add this to my saved trials
561 West Central Avenue
Delaware, Ohio 43015
(740) 615-1000
Principal Investigator: Timothy D. Moore
Phone: 740-615-0227
Delaware Health Center-Grady Cancer Center As the center of healthcare in Delaware County, Grady Memorial...
?
mi
from
Delaware, OH
Click here to add this to my saved trials
561 W. Central Avenue
Delaware, Ohio 43015
(740) 615-1000
Principal Investigator: Timothy D. Moore
Phone: 740-615-2403
Grady Memorial Hospital As the center of healthcare in Delaware County, Grady Memorial Hospital is...
?
mi
from
Delaware, OH
Click here to add this to my saved trials
Dublin, California 94568
Principal Investigator: James H. Feusner
Phone: 925-875-1677
?
mi
from
Dublin, CA
Click here to add this to my saved trials
6401 France Ave S
Edina, Minnesota 55435
(952) 924-5000
Principal Investigator: David M. King
Phone: 952-993-1517
Fairview Southdale Hospital Fairview Health Services is an award-winning nonprofit health care system based in...
?
mi
from
Edina, MN
Click here to add this to my saved trials
Effingham, Illinois 62401
Principal Investigator: James R. Egner
Phone: 800-446-5532
?
mi
from
Effingham, IL
Click here to add this to my saved trials
Emeryville, California 94608
Principal Investigator: James H. Feusner
Phone: 510-835-9900
?
mi
from
Emeryville, CA
Click here to add this to my saved trials
Emeryville, California 94608
Principal Investigator: James H. Feusner
Phone: 510-629-6682
?
mi
from
Emeryville, CA
Click here to add this to my saved trials
1202 East Locust Street
Emmett, Idaho 83617
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Emmett, ID
Click here to add this to my saved trials
Evansville, Indiana 47713
Principal Investigator: James R. Egner
Phone: 877-654-0311
?
mi
from
Evansville, IN
Click here to add this to my saved trials
Fairway, Kansas 66205
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Fairway, KS
Click here to add this to my saved trials
165 North University Avenue
Farmington, Utah 84025
Principal Investigator: Benjamin N. Voorhies
Phone: 888-424-2100
?
mi
from
Farmington, UT
Click here to add this to my saved trials
550 Osborne Rd NE
Fridley, Minnesota 55432
(763) 236-5000
Principal Investigator: David M. King
Phone: 952-993-1517
Unity Hospital Unity Hospital is one of the Twin Cities
?
mi
from
Fridley, MN
Click here to add this to my saved trials
410 East Spruce Street
Garden City, Kansas 67846
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
?
mi
from
Garden City, KS
Click here to add this to my saved trials
Geneva, Illinois 60134
Principal Investigator: Arlene D'Souza
Phone: 630-315-1918
?
mi
from
Geneva, IL
Click here to add this to my saved trials
Goldsboro, North Carolina 27534
Principal Investigator: Nagesh H. Jayaram
Phone: 919-587-9077
?
mi
from
Goldsboro, NC
Click here to add this to my saved trials
2700 Wayne Memorial Dr
Goldsboro, North Carolina 27534
(919) 736-1110
Principal Investigator: Nagesh H. Jayaram
Phone: 919-731-6687
Wayne Memorial Hospital Wayne Memorial Hospital, an affiliate of Wayne Health Corporation, is home to...
?
mi
from
Goldsboro, NC
Click here to add this to my saved trials
2596 F Road
Grand Junction, Colorado 81501
Principal Investigator: Benjamin N. Voorhies
Phone: 970-644-4460
?
mi
from
Grand Junction, CO
Click here to add this to my saved trials
Great Bend, Kansas 67530
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
?
mi
from
Great Bend, KS
Click here to add this to my saved trials
1117 29th St S
Great Falls, Montana 59405
(406) 771-7300
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Benefis Healthcare- Sletten Cancer Institute Benefis Hospitals has 516 beds at its two campuses (that...
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
1400 29th Street South
Great Falls, Montana 59405
406-454-2171
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Great Falls Clinic Founded in 1917, the Great Falls Clinic is the fourth oldest medical...
?
mi
from
Great Falls, MT
Click here to add this to my saved trials
80 Seymour St
Hartford, Connecticut 6102
(860) 545-5000
Principal Investigator: Omar Eton
Phone: 860-545-5363
The Hartford Hospital Hartford Hospital is the major teaching hospital affiliated with the University of...
?
mi
from
Hartford, CT
Click here to add this to my saved trials
2220 Canterbury Drive
Hays, Kansas 67601
785.623.5000
Principal Investigator: Gary C. Doolittle
Phone: 785-623-5774
Hays Medical Center Hays Medical Center is a private, not-for-profit hospital formed by the 1991...
?
mi
from
Hays, KS
Click here to add this to my saved trials
Helena, Montana 59601
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
?
mi
from
Helena, MT
Click here to add this to my saved trials
Independence, Missouri 64057
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
?
mi
from
Independence, MO
Click here to add this to my saved trials
Jacksonville, North Carolina 28546
Principal Investigator: Nagesh H. Jayaram
Phone: 910-353-0824
?
mi
from
Jacksonville, NC
Click here to add this to my saved trials
Jacksonville, North Carolina 28546
Principal Investigator: Nagesh H. Jayaram
Phone: 910-353-0824
?
mi
from
Jacksonville, NC
Click here to add this to my saved trials
Joplin, Missouri 64804
Principal Investigator: Jay W. Carlson
Phone: 417-556-3074
?
mi
from
Joplin, MO
Click here to add this to my saved trials
1102 W 32nd St
Joplin, Missouri 64804
(417) 347-1111
Principal Investigator: Jay W. Carlson
Phone: 417-347-4030
Freeman Health System Freeman in Joplin, Missouri, is a 485-bed, three-hospital system providing comprehensive healthcare...
?
mi
from
Joplin, MO
Click here to add this to my saved trials
310 Sunnyview Ln
Kalispell, Montana 59901
(406) 752-5111
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Kalispell Regional Medical Center Nestled in the beautiful Flathead Valley of Northwestern Montana, Kalispell Regional...
?
mi
from
Kalispell, MT
Click here to add this to my saved trials
Kansas City, Kansas 66112
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
Kansas City, Kansas 66160
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
Kansas City, Missouri 64131
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Kansas City, Missouri 64154
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
2301 Holmes
Kansas City, Missouri 64108
816-404-1000
Principal Investigator: Gary C. Doolittle
Phone: 816-404-4375
Truman Medical Center Located in the heart of downtown Kansas City, TMC Hospital Hill is...
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
2316 E Meyer Blvd
Kansas City, Missouri 64132
(816) 276-4000
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
Research Medical Center Research Medical Center offers hospital and health clinic services across three Kansas...
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Lake Forest, Illinois 60045
Principal Investigator: Sunandana Chandra
Phone: 312-695-1301
?
mi
from
Lake Forest, IL
Click here to add this to my saved trials
401 N Ewing St
Lancaster, Ohio 43130
(740) 687-8000
Principal Investigator: Timothy D. Moore
Phone: 740-687-8863
Fairfield Medical Center We are people you know offering care you trust. Serving more than...
?
mi
from
Lancaster, OH
Click here to add this to my saved trials
Lee's Summit, Missouri 64064
Principal Investigator: Gary C. Doolittle
Phone: 913-945-7552
?
mi
from
Lee's Summit, MO
Click here to add this to my saved trials
Lenexa, Kansas 66219
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
?
mi
from
Lenexa, KS
Click here to add this to my saved trials
Lenexa, Kansas 66219
Principal Investigator: Rakesh Gaur
Phone: 913-948-5588
?
mi
from
Lenexa, KS
Click here to add this to my saved trials
500 E 1400 N
Logan, Utah 84341
(435) 716-1000
Principal Investigator: Tawnya L. Bowles
Phone: 435-716-6400
Logan Regional Hospital Logan Regional Hospital is a nonprofit, full-service regional medical center and level...
?
mi
from
Logan, UT
Click here to add this to my saved trials
1983 Marengo St
Los Angeles, California 90033
(323) 226-2622
Principal Investigator: Gino K. In
Phone: 323-865-0451
Los Angeles County-USC Medical Center The origins of LAC+USC Medical Center date back to 1878,...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
1441 Eastlake Ave
Los Angeles, California 90033
(323) 865-3000
Principal Investigator: Gino K. In
Phone: 323-865-0451
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90095
Principal Investigator: Bartosz Chmielowski
Phone: 888-798-0719
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Mansfield, Ohio 44903
Principal Investigator: Timothy D. Moore
Phone: 419-526-8018
?
mi
from
Mansfield, OH
Click here to add this to my saved trials
Maple Grove, Minnesota 55369
Principal Investigator: David M. King
Phone: 952-993-1517
?
mi
from
Maple Grove, MN
Click here to add this to my saved trials
Maplewood, Minnesota 55109
Principal Investigator: David M. King
Phone: 952-993-1517
?
mi
from
Maplewood, MN
Click here to add this to my saved trials
1575 Beam Ave
Maplewood, Minnesota 55109
(651) 232-7000
Principal Investigator: David M. King
Phone: 888-823-5923
Saint John's Hospital - Healtheast St. John's Hospital is committed to providing superior health care...
?
mi
from
Maplewood, MN
Click here to add this to my saved trials
401 Matthew St
Marietta, Ohio 45750
(740) 374-1455
Principal Investigator: Timothy D. Moore
Phone: 800-523-3977
Marietta Memorial Hospital We are 2,600 strong and the county
?
mi
from
Marietta, OH
Click here to add this to my saved trials
Marion, Ohio 43302
Principal Investigator: Timothy D. Moore
Phone: 614-488-2118
?
mi
from
Marion, OH
Click here to add this to my saved trials
2500 Alhambra Ave
Martinez, California 94553
(925) 370-5000
Principal Investigator: James H. Feusner
Phone: 925-957-5400
Contra Costa Regional Medical Center Contra Costa Health Services is the largest department of County...
?
mi
from
Martinez, CA
Click here to add this to my saved trials
Mattoon, Illinois 61938
Principal Investigator: James R. Egner
Phone: 800-446-5532
?
mi
from
Mattoon, IL
Click here to add this to my saved trials
Meridian, Idaho 83642
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Meridian, ID
Click here to add this to my saved trials
Miami Beach, Florida 33140
Principal Investigator: Jose Lutzky
Phone: 305-674-2625
?
mi
from
Miami Beach, FL
Click here to add this to my saved trials
Minneapolis, Minnesota 55414
Principal Investigator: David M. King
Phone: 952-993-1517
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
Minneapolis, Minnesota 55454
Principal Investigator: David M. King
Phone: 952-993-1517
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
800 E 28th St
Minneapolis, Minnesota 55407
(612) 863-4000
Principal Investigator: David M. King
Phone: 952-993-1517
Abbott Northwestern Hospital Our hospital has a long and proud history as a health care...
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
Missoula, Montana 59801
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
?
mi
from
Missoula, MT
Click here to add this to my saved trials
Monroe, Michigan 48162
Principal Investigator: Abhijit B. Saste
Phone: 888-823-5923
?
mi
from
Monroe, MI
Click here to add this to my saved trials
Monticello, Minnesota 55362
Principal Investigator: David M. King
Phone: 952-993-1517
?
mi
from
Monticello, MN
Click here to add this to my saved trials
1 Good Samaritan Way
Mount Vernon, Illinois 62864
(618) 242-4600
Principal Investigator: Jay W. Carlson
Phone: 618-242-4600
Good Samaritan Regional Health Center St. Mary's Good Samaritan, Incorporated (SMGSI) was created in 1996...
?
mi
from
Mount Vernon, IL
Click here to add this to my saved trials
1330 Coshocton Ave
Mount Vernon, Ohio 43050
(740) 393-9000
Principal Investigator: Timothy D. Moore
Phone: 740-393-9000
Knox Community Hospital A community-owned, 115-bed, not-for-profit hospital located in Mount Vernon, Ohio (approximately 40...
?
mi
from
Mount Vernon, OH
Click here to add this to my saved trials
5121 S Cottonwood St
Murray, Utah 84157
(801) 507-7000
Principal Investigator: Tawnya L. Bowles
Phone: 801-507-3950
Intermountain Medical Center Intermountain Medical Center is one of the most technologically advanced and patient-friendly...
?
mi
from
Murray, UT
Click here to add this to my saved trials
1512 12th Avenue Road
Nampa, Idaho 83686
Principal Investigator: Benjamin T. Marchello
Phone: 734-712-3671
?
mi
from
Nampa, ID
Click here to add this to my saved trials
501 Hospital Rd
New Richmond, Wisconsin 54017
(715) 243-2800
Principal Investigator: David M. King
Phone: 952-993-1517
Cancer Center of Western Wisconsin For community members who need effective and compassionate cancer care,...
?
mi
from
New Richmond, WI
Click here to add this to my saved trials