Explanted Lung Tissues With Pulmonary Fibrosis



Status:Recruiting
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:11/2/2018
Start Date:February 2006
End Date:December 2021
Contact:Robert Guzy, MD
Email:rguzy@medicine.bsd.uchicago.edu

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Utilization of Explanted Lungs for Isolation of Tissue Samples and Primary Cell Lines to Study Pulmonary Fibrosis

The goal of this study is to use the tissues from the explanted lungs in order to better
study the cause of pulmonary fibrosis at a cellular level.

Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become
replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a
reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing
a permanent loss of the tissue's ability to carry oxygen into the bloodstream.

We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung
tissue from patients with pulmonary fibrosis.

Inclusion Criteria:

- all patients awaiting lung transplant

Exclusion Criteria:

- all who will not give consent
We found this trial at
1
site
5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
Phone: 773-702-6156
University of Chicago One of the world's premier academic and research institutions, the University of...
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