Influence of Central Obesity on the Esophageal Epithelial Barrier
| Status: | Recruiting |
|---|---|
| Conditions: | Gastroesophageal Reflux Disease |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 1/9/2019 |
| Start Date: | November 2016 |
| End Date: | April 2020 |
| Contact: | Michele Johnson, CCRP |
| Email: | johnson.michele@mayo.edu |
| Phone: | 507-255-8692 |
This study is being done to help understand why some people with an increased amount of
central obesity, without gastroesophageal reflux, develop changes to the lining of their
esophagus that can potentially lead to esophageal adenocarcinoma (cancer).
central obesity, without gastroesophageal reflux, develop changes to the lining of their
esophagus that can potentially lead to esophageal adenocarcinoma (cancer).
Inclusion Criteria:
Participants who are undergoing clinically indicated upper endoscopy with Bravo ambulatory
pH capsule (off reflux medications for 7 days), in the Esophageal Clinic at Mayo Clinic.
Exclusion Criteria:
1. Pre-existing or suspected Barrett's Esophagus (> 1cm of columnar mucosa in esophagus
on endoscopy
2. Oral anticoagulation precluding endoscopic biopsies
3. Patients with known hypersensitivity to fluorescein sodium.
We found this trial at
1
site
Rochester, Minnesota 55905
Principal Investigator: Prasad G Iyer, MD
Phone: 507-293-5307
Click here to add this to my saved trials
