Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders



Status:Recruiting
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:8/30/2018
Start Date:March 1, 2017
End Date:July 2021
Contact:Michelle Cusumano, BA
Email:michelle.cusumano@yale.edu
Phone:(203) 450-9944

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Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment
for reducing alcohol use

Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment
for reducing alcohol use through an 8-week randomized trial with 6-month follow-up. Our
primary hypothesis is that either form of CBT will be more effective than standard treatment
at increasing the percentage of days abstinent during treatment (8 weeks) and through the
follow-up (6 months), assessed via Timeline FollowBack interviews.

Inclusion Criteria:

Individuals will be included who:

- Are 18 years of age or older.

- Are applying for outpatient alcohol treatment and meet current DSM-5 criteria for
alcohol use disorder, consuming at least 14/7 drinks (men/women) per week with at
least 4 heavy drinking days reported in the past 28 days,

- Are sufficiently stable for 8 weeks of outpatient treatment and can commit to a
6-month follow-up

- Are willing to provide locator information for follow-up, and

- Are fluent in English and have a 6th grade or higher reading level.

Exclusion Criteria:

Individuals will be excluded who:

- Have an untreated bipolar or schizophrenic disorder,

- Have a current legal case pending such that incarceration during the 8-week protocol
is likely,

- Have been prescribed an alcohol pharmacotherapy (e.g., disulfiram, naltrexone) within
the past two weeks, or

- Are physically dependent on alcohol, opioids or benzodiazepenes such that immediate
medical detoxification is necessary for safety purposes (individuals demonstrating
significant withdrawal symptoms would be eligible for re-screening following brief
medical detoxification, which is arranged by RCS staff at triage).
We found this trial at
2
sites
140 John Street
Bridgeport, Connecticut 06601
Principal Investigator: Brian Kiluk, PhD
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Bridgeport, CT
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New Haven, Connecticut 06511
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New Haven, CT
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