Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors



Status:Recruiting
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:40 - 70
Updated:5/5/2018
Start Date:April 2016
End Date:March 2019
Contact:Britta MacAlpine
Email:Britta.MacAlpine@uvmhealth.org
Phone:802-735-6509

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Trial Summary
Trial Overview
Inclusion Criteria
Exercise training has beneficial effects in cancer survivors to minimize some of the side
effects of cancer and its treatment and improve long-term prognosis, but there are numerous
hurdles for individuals diagnosed with, and being treated for, cancer to participate in
exercise programs. The goal of this research study is to begin to evaluate whether exercise
training via neuromuscular electrical stimulation (NMES) has beneficial effects on skeletal
muscle size and function in cancer survivors.


Inclusion Criteria:

1. stage I, II or III breast cancer

2. receiving neoadjuvant or adjuvant chemotherapy with or without radiation

3. a body mass index <35 kg/m2.

Exclusion Criteria:

1. metastatic disease, a prior history of cancer, excluding non-melanoma skin cancer, or
prior receipt of chemotherapy

2. autoimmune, vascular or neuromuscular disease that could alter skeletal muscle

3. prior knee or hip replacement

4. contraindications for use of neuromuscular electrical stimulation, including an
implanted cardiac defibrillator or pacemaker, lower extremity blood clot or
coagulopathy

5. pregnancy
We found this trial at
1
site
University of Vermont College of Medicine
1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
Phone: 802-735-6509
?
mi
from
Burlington, VT
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