Psoriasis Longitudinal Assessment and Registry (PSOLAR)



Status:Recruiting
Conditions:Arthritis, Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery, Rheumatology
Healthy:No
Age Range:18 - 99
Updated:3/27/2019
Start Date:June 21, 2007
End Date:December 1, 2029
Contact:Use link at the bottom of the page to see if you qualify for an enrolling site (see list). If you still have questions:
Email:JNJ.CT@sylogent.com

Use our guide to learn which trials are right for you!

A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and
guselkumab in patients with plaque psoriasis, and other all forms of psoriasis (such as
plaque psoriasis and psoriatic arthritis occurring together). The registry study will track
the behavior of the disease in response to other therapies, such as other biologic drugs. The
registry will also evaluate clinical outcomes; disease characteristics, including physician
reported assessment of psoriatic arthritis (PsA); quality of life, and potential risks for
patients who may receive standard therapies for psoriasis.

PSOLAR is an 8 year registry study. A registry is an observational study that evaluates the
status of a disease. This registry study will only include patients who volunteer to take
part. About 4000 infliximab-exposed patients, 4000 ustekinumab-exposed patients and as well
as a comparable number of patients (4000) on other standard of care psoriasis therapies (e.g.
Etanercept) and/or psoriasis treatments (e.g. topical or light therapy treatments) will take
part in the registry study, internationally. Additionally, enrollment will be opened to
include at least 2,000 guselkumab-exposed patients and up to 2,000 patients exposed to IL-17
inhibitors (example, secukinumab, ixekizumab, brodalumab). The Registry does not require any
study-specific testing, but may capture test information (e.g. laboratory tests, X-rays) that
are collected as part of normal routine care for the registry program. Patient information
will be collected at the enrollment visit and about every 6 months thereafter. At enrollment,
information on demographics (e.g. gender, race, date of birth), medical history and family
medical history, details of past and current psoriasis treatments (e.g. infliximab and
standard therapy), and current medication regimens will be collected. Clinical follow-up will
be based on observations from physical examination, clinical disease status, Quality of Life
assessment (e.g. Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, EQ-5D
(EuroQoL-5D is a Quality of Life Questionnaire) Health Questionnaire Scale,
Employment/Productivity Health Economic Questionnaire), current medications, and any adverse
events/problems reported. During each six -month follow-up visit with the study doctor,
information collected will include observations from physical examination, updates on
clinical disease status, Quality of life assessments, medications and adverse
events/problems. No study agents will be administered in this registry. All patients will
receive standard of care treatments prescribed by the patient's physician.

Inclusion Criteria:

- Have a diagnosis of psoriasis

- Are candidates for, or are currently receiving conventional systemic agents (eg,
methotrexate, acitretin, cyclosporine or systemic psoralen drug in combination with
Ultraviolet A light [PUVA]) or biologic therapy for psoriasis including those with
chronic severe (extensive and/or disabling) plaque psoriasis who may be treated with
infliximab or those with moderate to severe plaque psoriasis who may be treated with
ustekinumab, guselkumab, or another biologic agent

- Ability to understand and sign an informed consent form

- Are willing to participate in regular follow-up visits

Exclusion Criteria:

- Refuse to consent or are unwilling to respond to request for a long term information
within the required time frame

- Are participating or have already planned to participate in a clinical trial with
non-marketed investigational agents or are participating in a Centocor-sponsored
clinical trial with marketed agents
We found this trial at
224
sites
Suffern, New York 10901
?
mi
from
Suffern, NY
Click here to add this to my saved trials
75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
?
mi
from
Boston, MA
Click here to add this to my saved trials
1601 Northwest 12th Avenue
Miami, Florida 33136
(305) 243-6545
University of Miami Miller School of Medicine The University of Miami Leonard M. Miller School...
?
mi
from
Miami, FL
Click here to add this to my saved trials
201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
University of Utah Research is a major component in the life of the U benefiting...
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
Akron, Ohio 44313
?
mi
from
Akron, OH
Click here to add this to my saved trials
?
mi
from
Akron, OH
Click here to add this to my saved trials
Alpharetta, Georgia 30022
?
mi
from
Alpharetta, GA
Click here to add this to my saved trials
Ann Arbor, Michigan 48103
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Arlington, Texas 76011
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Arlington, Texas 76011
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Arlington, Virginia 22204
?
mi
from
Arlington, VA
Click here to add this to my saved trials
Atlanta, Georgia 30309
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Atlanta, Georgia 30342
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Auburn, New York 13021
?
mi
from
Auburn, NY
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Bakersfield, California 93309
?
mi
from
Bakersfield, CA
Click here to add this to my saved trials
Bartlett, Tennessee 38134
?
mi
from
Bartlett, TN
Click here to add this to my saved trials
Bay Pines, Florida 33744
?
mi
from
Bay Pines, FL
Click here to add this to my saved trials
Belleville, New Jersey 07109
?
mi
from
Belleville, NJ
Click here to add this to my saved trials
Beverly Hills, California 90211
?
mi
from
Beverly Hills, CA
Click here to add this to my saved trials
Birmingham, Alabama 35205
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Birmingham, Alabama 35233
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Birmingham, Georgia 35242
?
mi
from
Birmingham, GA
Click here to add this to my saved trials
Boca Raton, Florida 33428
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Boca Raton, Florida 33431
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Boston, Massachusetts
?
mi
from
Boston, MA
Click here to add this to my saved trials
Boston, Massachusetts 02114
?
mi
from
Boston, MA
Click here to add this to my saved trials
Boynton Beach, Florida 33437
?
mi
from
Boynton Beach, FL
Click here to add this to my saved trials
Bridgeport, Connecticut 06606
?
mi
from
Bridgeport, CT
Click here to add this to my saved trials
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
?
mi
from
Bronx, NY
Click here to add this to my saved trials
?
mi
from
Buenos Aires,
Click here to add this to my saved trials
Calhoun, Georgia 30701
?
mi
from
Calhoun, GA
Click here to add this to my saved trials
Carrollton, Georgia 30117
?
mi
from
Carrollton, GA
Click here to add this to my saved trials
Catonsville, Maryland 21228
?
mi
from
Catonsville, MD
Click here to add this to my saved trials
Cedar Hill, Texas 75104
?
mi
from
Cedar Hill, TX
Click here to add this to my saved trials
Champaign, Illinois 61820
?
mi
from
Champaign, IL
Click here to add this to my saved trials
Chapel Hill, North Carolina 27516
?
mi
from
Chapel Hill, NC
Click here to add this to my saved trials
Charleston, South Carolina 29414
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Chesterfield, Missouri 63017
?
mi
from
Chesterfield, MO
Click here to add this to my saved trials
Chicago, Illinois 49201
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Cincinnati, Ohio 45236
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Clarkston, Michigan 48346
?
mi
from
Clarkston, MI
Click here to add this to my saved trials
Clinton Township, Michigan 48038
?
mi
from
Clinton Township, MI
Click here to add this to my saved trials
Clovis, California 93612
?
mi
from
Clovis, CA
Click here to add this to my saved trials
170 South Parkside Drive
Colorado Springs, Colorado 80910
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Columbus, Ohio 43220
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Commack, New York 11725
?
mi
from
Commack, NY
Click here to add this to my saved trials
Conyers, Georgia 30012
?
mi
from
Conyers, GA
Click here to add this to my saved trials
Coos Bay, Oregon 97420
?
mi
from
Coos Bay, OR
Click here to add this to my saved trials
Coral Gables, Florida 33134
?
mi
from
Coral Gables, FL
Click here to add this to my saved trials
Coral Gables, Florida 33134
?
mi
from
Coral Gables, FL
Click here to add this to my saved trials
Corbin, Kentucky 40701
?
mi
from
Corbin, KY
Click here to add this to my saved trials
Coupeville, Washington 98239
?
mi
from
Coupeville, WA
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Dayton, Ohio 45408
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Dayton, Ohio 45415
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Delaware, Ohio 43015
?
mi
from
Delaware, OH
Click here to add this to my saved trials
Delray Beach, Florida 33483
?
mi
from
Delray Beach, FL
Click here to add this to my saved trials
Dunedin, Florida 34698
?
mi
from
Dunedin, FL
Click here to add this to my saved trials
?
mi
from
Eagan, MN
Click here to add this to my saved trials
East Windsor, New Jersey 08520
?
mi
from
East Windsor, NJ
Click here to add this to my saved trials
Elmhurst, New York 11373
?
mi
from
Elmhurst, NY
Click here to add this to my saved trials
Englewood, Colorado 80112
?
mi
from
Englewood, CO
Click here to add this to my saved trials
Evansville, Indiana 47725
?
mi
from
Evansville, IN
Click here to add this to my saved trials
Exton, Pennsylvania 19341
?
mi
from
Exton, PA
Click here to add this to my saved trials
Farmington, Connecticut 06030
?
mi
from
Farmington, CT
Click here to add this to my saved trials
Farmington, Michigan 48334
?
mi
from
Farmington, MI
Click here to add this to my saved trials
Flint, Michigan 48507
?
mi
from
Flint, MI
Click here to add this to my saved trials
Florence, Alabama 35630
?
mi
from
Florence, AL
Click here to add this to my saved trials
Fort Gratiot, Michigan 48059
?
mi
from
Fort Gratiot, MI
Click here to add this to my saved trials
Fort Mill, South Carolina 29708
?
mi
from
Fort Mill, SC
Click here to add this to my saved trials
Fort Washington, Pennsylvania 19034
?
mi
from
Fort Washington, PA
Click here to add this to my saved trials
Fountain Valley, California 92708
?
mi
from
Fountain Valley, CA
Click here to add this to my saved trials
Fresno, California 93720
?
mi
from
Fresno, CA
Click here to add this to my saved trials
?
mi
from
Gahanna, OH
Click here to add this to my saved trials
920 North Hamilton Road
Gahanna, Ohio 43230
?
mi
from
Gahanna, OH
Click here to add this to my saved trials
Garden City, New York 11530
?
mi
from
Garden City, NY
Click here to add this to my saved trials
Grand Blanc, Michigan 48439
?
mi
from
Grand Blanc, MI
Click here to add this to my saved trials
Grand Rapids, Michigan 49503
?
mi
from
Grand Rapids, MI
Click here to add this to my saved trials
Green Bay, Wisconsin 54313
?
mi
from
Green Bay, WI
Click here to add this to my saved trials
Greeneville, Tennessee 37745
?
mi
from
Greeneville, TN
Click here to add this to my saved trials
Helena, Montana 59601
?
mi
from
Helena, MT
Click here to add this to my saved trials
Henderson, Nevada 89052
?
mi
from
Henderson, NV
Click here to add this to my saved trials
Hickory, North Carolina 28601
?
mi
from
Hickory, NC
Click here to add this to my saved trials
Hoboken, New Jersey 07030
?
mi
from
Hoboken, NJ
Click here to add this to my saved trials
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
Houston, Texas 77008
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Houston, Texas 77082
?
mi
from
Houston, TX
Click here to add this to my saved trials
Huntington, New York 11743
?
mi
from
Huntington, NY
Click here to add this to my saved trials
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Huntsville, Alabama 35801
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
545 Barnhill Dr
Indianapolis, Indiana 46201
(317) 274-8157
Indiana University Medical Center Indiana University Health is Indiana
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Indianapolis, Indiana 46256
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Indianapolis, Indiana 46260
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Jacksonville, Florida 32207
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Jacksonville, Florida 32256
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials