Psoriasis Longitudinal Assessment and Registry (PSOLAR)



Status:Recruiting
Conditions:Arthritis, Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery, Rheumatology
Healthy:No
Age Range:18 - 99
Updated:3/27/2019
Start Date:June 21, 2007
End Date:December 1, 2029
Contact:Use link at the bottom of the page to see if you qualify for an enrolling site (see list). If you still have questions:
Email:JNJ.CT@sylogent.com

Use our guide to learn which trials are right for you!

A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics

The purpose of this study is to further evaluate the safety of infliximab, ustekinumab, and
guselkumab in patients with plaque psoriasis, and other all forms of psoriasis (such as
plaque psoriasis and psoriatic arthritis occurring together). The registry study will track
the behavior of the disease in response to other therapies, such as other biologic drugs. The
registry will also evaluate clinical outcomes; disease characteristics, including physician
reported assessment of psoriatic arthritis (PsA); quality of life, and potential risks for
patients who may receive standard therapies for psoriasis.

PSOLAR is an 8 year registry study. A registry is an observational study that evaluates the
status of a disease. This registry study will only include patients who volunteer to take
part. About 4000 infliximab-exposed patients, 4000 ustekinumab-exposed patients and as well
as a comparable number of patients (4000) on other standard of care psoriasis therapies (e.g.
Etanercept) and/or psoriasis treatments (e.g. topical or light therapy treatments) will take
part in the registry study, internationally. Additionally, enrollment will be opened to
include at least 2,000 guselkumab-exposed patients and up to 2,000 patients exposed to IL-17
inhibitors (example, secukinumab, ixekizumab, brodalumab). The Registry does not require any
study-specific testing, but may capture test information (e.g. laboratory tests, X-rays) that
are collected as part of normal routine care for the registry program. Patient information
will be collected at the enrollment visit and about every 6 months thereafter. At enrollment,
information on demographics (e.g. gender, race, date of birth), medical history and family
medical history, details of past and current psoriasis treatments (e.g. infliximab and
standard therapy), and current medication regimens will be collected. Clinical follow-up will
be based on observations from physical examination, clinical disease status, Quality of Life
assessment (e.g. Dermatology Life Quality Index, Hospital Anxiety and Depression Scale, EQ-5D
(EuroQoL-5D is a Quality of Life Questionnaire) Health Questionnaire Scale,
Employment/Productivity Health Economic Questionnaire), current medications, and any adverse
events/problems reported. During each six -month follow-up visit with the study doctor,
information collected will include observations from physical examination, updates on
clinical disease status, Quality of life assessments, medications and adverse
events/problems. No study agents will be administered in this registry. All patients will
receive standard of care treatments prescribed by the patient's physician.

Inclusion Criteria:

- Have a diagnosis of psoriasis

- Are candidates for, or are currently receiving conventional systemic agents (eg,
methotrexate, acitretin, cyclosporine or systemic psoralen drug in combination with
Ultraviolet A light [PUVA]) or biologic therapy for psoriasis including those with
chronic severe (extensive and/or disabling) plaque psoriasis who may be treated with
infliximab or those with moderate to severe plaque psoriasis who may be treated with
ustekinumab, guselkumab, or another biologic agent

- Ability to understand and sign an informed consent form

- Are willing to participate in regular follow-up visits

Exclusion Criteria:

- Refuse to consent or are unwilling to respond to request for a long term information
within the required time frame

- Are participating or have already planned to participate in a clinical trial with
non-marketed investigational agents or are participating in a Centocor-sponsored
clinical trial with marketed agents
We found this trial at
224
sites
Williamsville, New York 14221
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Williamsville, NY
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75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Boston, MA
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1601 Northwest 12th Avenue
Miami, Florida 33136
(305) 243-6545
University of Miami Miller School of Medicine The University of Miami Leonard M. Miller School...
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Miami, FL
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201 Presidents Circle
Salt Lake City, Utah 84108
801) 581-7200
University of Utah Research is a major component in the life of the U benefiting...
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Salt Lake City, UT
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Akron, Ohio 44313
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Akron, OH
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Akron, OH
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Alpharetta, Georgia 30022
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Alpharetta, GA
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Ann Arbor, Michigan 48103
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Arlington, Texas 76011
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Arlington, TX
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Arlington, Texas 76011
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Arlington, TX
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Arlington, Virginia 22204
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Arlington, VA
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Atlanta, Georgia 30309
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Atlanta, GA
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Atlanta, Georgia 30342
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Atlanta, GA
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Auburn, New York 13021
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Auburn, NY
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Aventura, Florida 33180
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Aventura, FL
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Aventura, Florida 33180
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Bakersfield, California 93309
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Bartlett, Tennessee 38134
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Bartlett, TN
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Bay Pines, Florida 33744
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Bay Pines, FL
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Belleville, New Jersey 07109
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Belleville, NJ
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Beverly Hills, California 90211
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Birmingham, Alabama 35205
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Birmingham, AL
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Birmingham, Alabama 35233
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Birmingham, AL
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Birmingham, Georgia 35242
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Birmingham, GA
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Boca Raton, Florida 33428
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Boca Raton, Florida 33431
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Boston, Massachusetts
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Boston, MA
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Boston, Massachusetts 02114
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Boynton Beach, Florida 33437
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Bridgeport, Connecticut 06606
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Bristol, Tennessee 37620
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Bristol, TN
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Bronx, NY
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Buenos Aires,
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Calhoun, Georgia 30701
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Calhoun, GA
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Carrollton, Georgia 30117
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Catonsville, Maryland 21228
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Catonsville, MD
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Cedar Hill, Texas 75104
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Cedar Hill, TX
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Champaign, Illinois 61820
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Champaign, IL
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Chapel Hill, North Carolina 27516
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Charleston, South Carolina 29414
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Chesterfield, Missouri 63017
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Chicago, Illinois 49201
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Chicago, IL
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Cincinnati, Ohio 45236
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Clarkston, Michigan 48346
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Clinton Township, Michigan 48038
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Clinton Township, MI
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Clovis, California 93612
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Clovis, CA
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170 South Parkside Drive
Colorado Springs, Colorado 80910
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Colorado Springs, CO
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Columbus, Ohio 43220
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Columbus, OH
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Commack, New York 11725
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Commack, NY
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Conyers, Georgia 30012
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Conyers, GA
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Coos Bay, Oregon 97420
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Coos Bay, OR
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Coral Gables, Florida 33134
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Coral Gables, FL
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Coral Gables, Florida 33134
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Corbin, Kentucky 40701
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Corbin, KY
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Coupeville, Washington 98239
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Coupeville, WA
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Dallas, TX
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Dallas, Texas 75231
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Dayton, Ohio 45408
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Dayton, Ohio 45415
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Delaware, Ohio 43015
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Delray Beach, Florida 33483
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Dunedin, Florida 34698
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Eagan, MN
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East Windsor, New Jersey 08520
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Elmhurst, New York 11373
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Englewood, Colorado 80112
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Evansville, Indiana 47725
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Exton, Pennsylvania 19341
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Farmington, Connecticut 06030
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Farmington, Michigan 48334
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Flint, Michigan 48507
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Florence, Alabama 35630
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Florence, AL
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Fort Gratiot, Michigan 48059
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Fort Mill, South Carolina 29708
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Fort Washington, Pennsylvania 19034
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Fountain Valley, California 92708
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Fresno, California 93720
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Fresno, CA
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Gahanna, OH
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920 North Hamilton Road
Gahanna, Ohio 43230
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Garden City, New York 11530
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Garden City, NY
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Grand Blanc, Michigan 48439
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Grand Rapids, Michigan 49503
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Green Bay, Wisconsin 54313
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Greeneville, Tennessee 37745
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Helena, Montana 59601
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Helena, MT
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Henderson, Nevada 89052
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Hickory, North Carolina 28601
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Hoboken, New Jersey 07030
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Hollywood, FL
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Houston, Texas 77008
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Houston, Texas 77082
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Huntington, New York 11743
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Huntsville, Alabama 35801
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Huntsville, Alabama 35801
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545 Barnhill Dr
Indianapolis, Indiana 46201
(317) 274-8157
Indiana University Medical Center Indiana University Health is Indiana
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Indianapolis, Indiana 46256
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Indianapolis, IN
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Indianapolis, Indiana 46260
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Jacksonville, Florida 32207
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Jacksonville, Florida 32256
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Jacksonville, FL
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