Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab



Status:Completed
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 99
Updated:3/21/2019
Start Date:November 24, 2014
End Date:March 9, 2018

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Trial Summary
Trial Overview
Inclusion Criteria

A Multicenter, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of Evolocumab

The purpose of this study was to characterize the safety and tolerability of long-term
administration of evolocumab in adults with known coronary artery disease and
hypercholesterolemia.


Inclusion Criteria:

- Completed week 80 of study 20120153 (NCT01813422).

Exclusion Criteria:

- Did not complete investigational product in the 20120153 parent study

- Have an unstable medical condition, in the judgment of the investigator

- Known sensitivity to any of the products to be administered during dosing

- Currently enrolled in another investigational device or drug study (excluding
evolocumab (AMG 145) parent study), or less than 30 days since ending another
investigational device or drug study(s),or receiving other investigational agent(s)
We found this trial at
25
sites
Clinical Trial Facility in Columbia Maryland
Columbia, Maryland 21044
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Columbia, MD
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Clinical Trial Facility in Amarillo Texas
Amarillo, Texas
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Amarillo, TX
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Clinical Trial Facility in Bay City Michigan
Bay City, Michigan 48708
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Bay City, MI
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Clinical Trial Facility in Bethesda Maryland
Bethesda, Maryland
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Bethesda, MD
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Clinical Trial Facility in Canton Ohio
Canton, Ohio 44718
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Canton, OH
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Clinical Trial Facility in Columbia Missouri
Columbia, Missouri 65201
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Columbia, MO
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Clinical Trial Facility in Covington Louisiana
Covington, Louisiana 70433
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Covington, LA
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Clinical Trial Facility in Dallas Texas
Dallas, Texas 75390
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Dallas, TX
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Clinical Trial Facility in Duluth Minnesota
Duluth, Minnesota
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Duluth, MN
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Clinical Trial Facility in Fargo North Dakota
Fargo, North Dakota 58122
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Fargo, ND
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Clinical Trial Facility in Huntsville Alabama
Huntsville, Alabama 35801
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from
Huntsville, AL
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Clinical Trial Facility in Jacksonville Florida
Jacksonville, Florida 32209
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Jacksonville, FL
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Clinical Trial Facility in La Plata Buenos Aires
La Plata, Buenos Aires
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La Plata,
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Clinical Trial Facility in Lexington Kentucky
Lexington, Kentucky
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Lexington, KY
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Clinical Trial Facility in Long Beach California
Long Beach, California 90806
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Long Beach, CA
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Clinical Trial Facility in Midland Michigan
Midland, Michigan 48640
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from
Midland, MI
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Clinical Trial Facility in Mobile Alabama
Mobile, Alabama
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from
Mobile, AL
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Clinical Trial Facility in Munster Indiana
Munster, Indiana 46321
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Munster, IN
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Clinical Trial Facility in Oak Ridge Tennessee
Oak Ridge, Tennessee 37830
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from
Oak Ridge, TN
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Clinical Trial Facility in Ridgewood New Jersey
Ridgewood, New Jersey 07450
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Ridgewood, NJ
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Clinical Trial Facility in Saint Cloud Minnesota
Saint Cloud, Minnesota
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Saint Cloud, MN
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Clinical Trial Facility in San Diego California
San Diego, California
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San Diego, CA
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Clinical Trial Facility in Toledo Ohio
Toledo, Ohio 43608
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Toledo, OH
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Clinical Trial Facility in Torrance California
Torrance, California
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Torrance, CA
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Clinical Trial Facility in Wichita Falls Texas
Wichita Falls, Texas 76301
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Wichita Falls, TX
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