Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP Trial



Status:Enrolling by invitation
Conditions:Cardiology, Hospital
Therapuetic Areas:Cardiology / Vascular Diseases, Other
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:October 2014
End Date:December 2015

Use our guide to learn which trials are right for you!

The purpose of this study is to evaluate the impact that the Venus 1000 non-invasive CVP
system has on the management of emergency department (ED) patients with fluid sensitive
conditions.

The ability to non-invasively, accurately, and continuously measure CVP to assess the
preload status of ED patients could lead to its inclusion into existing protocols (similar
to EGDT), or the development of novel protocols for the treatment of patients with fluid
sensitive conditions. The majority of other non-invasive measures of preload, such as
ultrasound of the inferior vena cava or the passive leg raise technique are not continuous
measures and require some type of effort or skill on the part of the clinician. Continuous
methods of assessing preload include CVP measurement through a central venous catheter,
esophageal Doppler monitoring, and pulse contour analysis via arterial catheter monitoring,
all of which involve invasive procedures.

The Venus CVP device is non-invasive and has continuous monitoring capabilities. The data
acquired from this project will allow us to determine whether emergency physicians will, in
practice, utilize the information provided by a non-invasive CVP monitoring device to assist
in the management of their patients with severe sepsis or acute HF.

Inclusion Criteria:

- Age 18 years old or greater

- English speaking

- Clinical diagnosis of: 1) Severe Sepsis, or 2) Acute Heart Failure

Exclusion Criteria:

- Traumatic injuries

- Active bleeding

- Pregnancy

- Prisoners

- Central venous catheter placement in the internal jugular or subclavian veins

- Bilateral external jugular vein catheterizations

- Concurrent enrollment into an interventional clinical trial that may affect subject
treatment
We found this trial at
1
site
Detroit, Michigan 48202
?
mi
from
Detroit, MI
Click here to add this to my saved trials