Deep Brain Stimulation (DBS) Data Base Study

Status:Enrolling by invitation
Conditions:Parkinsons Disease
Therapuetic Areas:Neurology
Age Range:18 - Any
Start Date:April 2013
End Date:December 2017

Use our guide to learn which trials are right for you!

The primary goal of this study is to evaluate and compare outcomes, trends, and
effectiveness of both awake and asleep Deep Brain Stimulation (DBS) surgical treatments,
target selection, targeting accuracy and outcomes in patients with Parkinson's disease and
Essential tremor.

Deep Brain Stimulation (DBS) surgery is a treatment that can improve some of the motor
symptoms associated with several movement disorder diseases. DBS is recommended for patients
with Parkinson's disease who respond well to medication, but still experience frequent
wearing off of medications with return of symptoms. Patients may also be experiencing
troubling medication side effects such as dyskinesias, sleepiness, hallucinations,
confusion, and behavioral/personality changes. DBS is also used for patients with Essential
tremor who have undergone long trials of medication therapy and are still symptomatic. The
goal of DBS surgery is to capture that best response to medication and hold it through the
day. The Food and Drug Administration (FDA) approved DBS as a treatment for essential tremor
in 1997 and for Parkinson's disease in 2002.

The goal of DBS surgery is to improve the quality of life of patients and their families by
reducing motor symptoms such as slowness, stiffness and tremor and possibly reducing
medication. In order to help with our understanding of its effects, we will collect
information on patients who will be undergoing or have undergone DBS surgery.

St. Joseph's Hospital and Medical Center / Barrow Neurological Institute is one of only a
few hospitals in the United States offering a new procedure known as asleep DBS surgery,
performed under general anesthesia, as well as the traditional awake DBS procedure;
therefore it is important that this new asleep surgery option be studied and compared to
awake DBS surgery.

Objectives include:

- Comparison of data collected for both the awake and asleep DBS procedures during the
pre-operative and post-operative periods including testing, diagnosis, surgical
treatment, target accuracy, complications, motor function and quality of life outcomes.

- Comparison of the differential effects of STN and GPi DBS on gait and balance control

- Investigate the effects of DBS on the saccadic eye movements.

Inclusion Criteria:

- Clinical diagnosis for Parkinson's Disease or Essential Tremor

- Subject has undergone DBS surgery

Exclusion Criteria:

- Clinical diagnosis for Parkinson's Disease or Essential Tremor

- Subject has not undergone DBS surgery
We found this trial at
Phoenix, AZ
Click here to add this to my saved trials