Effects of Yoga and Cardiovascular Exercise on Smoking Motivation



Status:Active, not recruiting
Conditions:Smoking Cessation, Tobacco Consumers
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 55
Updated:1/25/2017
Start Date:August 2007
End Date:September 2017

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The overall purpose of this pilot study is to examine effects of Hatha yoga and
cardiovascular exercise on craving, mood, cue reactivity, and smoking behavior. Our
preliminary study indicated that a single session of either form of activity intervention
improved mood, and the yoga intervention appeared to decrease cravings to smoke. The
proposed study will extend this preliminary research in several ways.

First, the investigators will expand the exercise-based interventions from one to three
sessions, which will more closely resemble how these interventions may be used in the
context of smoking cessation. Second, the investigators will recruit smokers who are
motivated to quit smoking, further increasing the clinical relevance of the research.
Finally, the investigators will examine the effects of the interventions on actual smoking
behavior within and outside of the laboratory setting. This may appropriately be considered
a "proof of concept" study, as the investigators will not be powered to detect treatment
outcome (smoking cessation) differences, nor are the interventions designed to maximize
clinical smoking cessation outcomes.

Participants will be randomized to receive 3-sessions of yoga instruction, 3-sessions of
cardiovascular exercise, or to a no activity control group. Sessions will be scheduled to
occur approximately 7 days apart, with a minimum of 4 between sessions. Mood and craving
will be assessed before and after each session, and smoking behavior will be assessed
following each session. Finally, a detailed cue reactivity assessment will be conducted
prior to the first session and following the last session. Analyses will examine
intervention effects on craving, mood, cue reactivity, and smoking behavior. In addition,
the investigators will examine several potential mediators and moderators of intervention
effects on smoking behavior. Finally, the investigators will continue to examine the
feasibility and potential acceptability of each active intervention, to assist in developing
future clinical applications of these techniques in the context of smoking cessation.

Inclusion Criteria:

- Smoke at least 10 cigarettes per day

- Smoked regularly at least 2 years

- Carbon monoxide reading at least 8 ppm

- Interest in quitting smoking

- Able to read and understand the consent form and questionnaires

- Not currently practicing yoga

Exclusion Criteria:

- Current Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) (American
Psychiatric Association, 1994) psychosis

- Major depressive episode, manic episode, or panic disorder

- Current DSM-IV psychoactive substance dependence or use

- Current medication use that might affect physiological responses

- Current use of bupropion, varenicline, or nicotine-containing products other than
cigarettes

- Significant health problems that might compromise physiological data collection or be
contraindicated for moderate physical exercise or yoga

- Significant hearing or visual impairment; pregnant as determined by urine human
chorionic gonadotropin (hCG) test or nursing females

- Body mass index (BMI) 35 or greater
We found this trial at
1
site
12902 USF Magnolia Dr
Tampa, Florida 33612
(888) 663-3488
H. Lee Moffitt Cancer Center & Research Institute Moffitt Cancer Center in Tampa, Florida, has...
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Tampa, FL
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