Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease



Status:Enrolling by invitation
Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:15 - 45
Updated:4/21/2016
Start Date:September 1999
End Date:May 2016

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Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) II

The Division of Kidney Urology and Hematology Disease (DKUHD) of the National Institute of
Diabetes and Digestive and Kidney Diseases (NIDDK) funded a cooperative agreement (UO1) for
a consortium of participating clinical centers (PCCs) and a data coordinating and imaging
analysis center (DCIAC) to develop and implement studies to test whether imaging techniques
can provide accurate and reproducible markers of progression of renal disease in patients
with polycystic kidney disease.

The awarded participating clinical centers are Emory University, University of Kansas, and
Mayo Foundation (with a subcontract to the University of Alabama). The awarded DCIAC is
Washington University in St. Louis. Due to the relocation of the DCIAC P.I. from Washington
University to the University of Pittsburgh, the DCIAC for CRISP II is located at the
University of Pittsburgh.

The goal of the CRISP Study is to conduct a prospective, longitudinal trial to evaluate the
accuracy and validity of magnetic resonance imaging to determine disease progression in
ADPKD defined as a change in both renal and renal cyst volumes and renal function over time.

Inclusion Criteria:

1. CRISP I participants will be invited to participate in CRISP II. At entry into CRISP I
participants met a number of inclusion and exclusion criteria.

Exclusion Criteria:

1. Current psychiatric or addiction or non-compliance disorder that in the discretion of
the principal investigator indicates that the subject will not successfully complete
the study;

2. Current medical problem that in the discretion of the principal investigator would
make unsafe the participation in the study;

3. Inability to provide written informed consent
We found this trial at
5
sites
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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201 Dowman Dr
Atlanta, Georgia 30303
(404) 727-6123
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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Atlanta, GA
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4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
(412) 624-4141
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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Kansas City, Kansas
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Rochester, Minnesota 55905
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Rochester, MN
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