Efficacy Study of LIQUICURE™ to Treat Toe Nail Fungus

Inclusion Criteria:

- Nail fungal infection of at least one great toe [per visual assessment, positive KOH
preparation, and positive dermatophyte culture]

- Subjects who have target toenail showing 20-65% involvement as judged by the clinical
investigator

- 2 mm of clear nail proximally on great toenail / no lunula involvement

- Subject must be physically able to reach toes to clean them and apply product

- Subject is willing to discontinue use of other nail fungus treatment products and
nail cosmetic products for duration of this study

- Subject is willing and available to return for study follow up

- Ability of the subject or legal representative to understand and provide signed
consent for participating in the study

- Negative urine pregnancy test for women of child bearing age

- Females must be post menopausal or must agree to use approved contraceptives
(actions, devices or medications to prevent or reduce the likelihood of pregnancy)
throughout the study (Note: abstinence is NOT an accepted form of contraception)

Exclusion Criteria:

- Known hypersensitivity or allergy to the product materials

- Negative KOH preparation or dermatophyte culture

- Thickness of nail greater than 3 mm

- Enrollment in another investigational drug or product protocol that would interfere
with this study

- Continuation or use of other topical or pharmaceutical treatments for the condition;
a wash-out period of at least four weeks after discontinuation of a topical product
or 180 days after discontinuation of an oral product for treatment of nail fungus is
required

- Chronic disease, including: diabetes, psoriasis, immune deficiency, severe foot
injury, chronic vascular disease or any other condition that would decrease
circulation to the extremities at the discretion of the investigator Pregnant or
nursing females

- Investigators, Chesson personnel, or Chesson Scientific Advisory Board members or
their immediate family