HFCWO in Hospitalized Asthmatic Children



Status:Completed
Conditions:Asthma, Bronchitis
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any - 18
Updated:4/21/2016
Start Date:July 2008
End Date:July 2010

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High Frequency Chest Wall Oscillation in Hospital Management of Asthmatic Children

To determine whether or not high frequency chest wall oscillation (in the form of the
VestTM) is superior to regular asthma therapy in the management of children hospitalized
with moderate to severe asthma.

A historically controlled pilot study was conducted in pediatric patients 18 months to 18
years of age hospitalized with a diagnosis of asthma or reactive airway disease and admitted
to the pediatric intensive care unit. Upon receiving informed consent, patients were treated
with HFCWO therapy via the VEST. The primary endpoint was time to readiness for discharge,
lack of need for continued supportive care (e.g., intravenous fluid or oxygen), and
bronchodilator treatments spaced at least four hours apart.

Inclusion Criteria:

- Any pediatric patient between the ages of 18 months and 18 years admitted to Winthrop
University Hospital's pediatric floor or intensive care unit with a diagnosis of
asthma or reactive airway disease

Exclusion Criteria:

- Patients with chronic, comorbid respiratory conditions (e.g., cerebral palsy, cystic
fibrosis)

- Those who regularly use HFCWO

- Any patient exhibiting an absolute contraindication to HFCWO therapy

- Absolute contraindications to using HFCWO include head and neck injury prior to
stabilization, and active hemorrhage with hemodynamic instability
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Long Island, New York 11501
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