Effects of Chromium Picolinate on Food Intake



Status:Completed
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 50
Updated:4/21/2016
Start Date:April 2005
End Date:May 2007

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Effects of Chromium Picolinate on Food Intake, Satiety, and Eating Attitudes in Overweight Women With Food Cravings

The purpose of this study is to test the effects of chromium picolinate on food intake, food
cravings, eating attitudes, and appetite. If chromium picolinate is found to have a
beneficial impact on satiety and food intake, then this supplement may be an alternative or
adjunctive treatment for overweight people desiring to modify their food intake. The primary
hypothesis of this study is that among individuals who report being carbohydrate cravers,
chromium picolinate supplementation will reduce food intake during a test lunch meal and
produce greater satiety in comparison to a placebo.


Inclusion Criteria:

Inclusion criteria are:

1. Healthy female who has not been diagnosed with diabetes, cardiovascular illness, or
other chronic diseases,

2. Food craver, determined by self-reported craving for carbohydrates on two out of
three validated measures of food cravings,

3. > 18 years of age and < 50 years of age, and

4. Body mass index between 25 and 39.9 kg/m2. Participants will be scheduled for testing
during the luteal phase of their menstrual cycle to limit the confounding effect of
the menstrual cycle on energy intake. We will include women who are taking monophasic
oral contraceptives but will exclude other oral contraceptive regimens. Participants
with very irregular menstrual cycles will also be excluded because this irregularity
will make it very difficult to schedule testing during the luteal phase of the
menstrual cycle.

Exclusion Criteria:

Potential participants will be excluded for the following reasons:

1. Participants who report smoking cigarettes will be excluded because of the effects of
nicotine upon taste and appetite,

2. Participants who have a diagnosable eating disorder (i.e., anorexia or bulimia
nervosa) will also be excluded since intentional restriction of eating and binge
eating/overeating could increase the variability of the data,

3. Participants who report using diet pills will be excluded since diet pills may
potentially influence appetite, hunger, and/or satiety,

4. Participants will be excluded if they are taking anti-depressant medications,
anti-psychotic medications, or any medications that may potentially influence
appetite, hunger, and/or satiety,

5. Participants who are not determined to be carbohydrate cravers will be excluded,

6. Participants will also be excluded if they report any allergies to the foods that
will be used in the study.
We found this trial at
1
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6400 Perkins Rd
Baton Rouge, Louisiana 70808
(225) 763-2500
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