Fluorine F 18 FEQA in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer and in Healthy Participants



Status:Active, not recruiting
Conditions:Lung Cancer, Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:May 2004

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The Biodistribution of N-{4-[3'-[F-18] Fluoroethylphenyl)Amino]-6-quinazolinyl}-Acrylamide ([F-F18]FEQA) in Patients With Advanced Non-Small-Cell Lung Cancer (NSCLC) and in Healthy Subjects: A Pilot Study

RATIONALE: Fluorine F 18 FEQA may be an effective radioactive drug to use with positron
emission tomography (PET) scans.

PURPOSE: This clinical trial is studying the use of fluorine F 18 FEQA in patients with
stage III or stage IV non-small cell lung cancer and in healthy participants.

OBJECTIVES:

- Determine the biodistribution of fluorine F 18 FEQA in patients with stage III or IV
non-small cell lung cancer (NSCLC) and in healthy participants.

- Determine whether fluorine F 18 FEQA can be used as an imaging agent with positron
emission tomography in patients with stage III or IV NSCLC.

OUTLINE: This is a pilot study.

Patients and healthy participants receive fluorine F 18 FEQA IV and then undergo whole-body
dynamic scans comprising positron emission tomography.

Blood is collected during and after imaging to measure radioactivity.

PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.

Inclusion Criteria:

- Must meet 1 of the following criteria:

- Diagnosis of non-small cell lung cancer by CT scan, bone scan, or biopsy

- Stage III or IV disease

- Clinically assessed with

- Healthy participant

Exclusion Criteria:
We found this trial at
1
site
10833 Le Conte Avenue # 8-950
Los Angeles, California 90095
(310) 825-5268
Jonsson Comprehensive Cancer Center at UCLA In the late 1960s, a group of scientists and...
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mi
from
Los Angeles, CA
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