A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis



Status:Withdrawn
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:2 - Any
Updated:4/21/2016
Start Date:February 2007

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A Double-Blind, Randomized Controlled Trial of Voriconazole (VFEND®) Plus Micafungin (MYCAMINE™) Versus Voriconazole Plus Placebo in the Treatment of Patients With Proven or Probable Invasive Aspergillosis

To evaluate the therapeutic effectiveness of voriconazole + micafungin versus voriconazole
alone as primary therapy for invasive aspergillosis.


Inclusion Criteria:

- Proven, probable or possible invasive aspergillosis

- Patient is 2 years of age or older

Exclusion Criteria:

- The patient has been administered an antifungal agent (voriconazole, itraconazole,
posaconazole, caspofungin, micafungin, anidulafungin, amphotericin B, or lipid
formulation of amphotericin B) for >7 days immediately prior to randomization for
treatment of the Possible, Probable, or Proven invasive aspergillosis for which the
patient is being enrolled.

- The patient has been treated with voriconazole for > 7 days immediately prior to
randomization
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