Evaluation of a New Agent for Treatment of Advanced Stage Breast Cancer
| Status: | Completed |
|---|---|
| Conditions: | Breast Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | April 2006 |
| End Date: | November 2008 |
Phase 2 Study to Investigate the Efficacy and Safety of ZK-Epothilone (ZK-Epo; ZK 219477) in Patients With Metastatic Breast Cancer
The purpose of this study is to evaluate whether treatment with a new drug called
ZK-Epothilone (ZK-Epo) in patients with metastatic breast cancer helps to decrease or stop
tumor growth.
ZK-Epothilone (ZK-Epo) in patients with metastatic breast cancer helps to decrease or stop
tumor growth.
This study has previously been registered by Berlex, Inc. Berlex, Inc. has been renamed to
Bayer HealthCare Pharmaceuticals, Inc.Bayer HealthCare Pharmaceuticals, Inc.is the sponsor
of this study.
Bayer HealthCare Pharmaceuticals, Inc.Bayer HealthCare Pharmaceuticals, Inc.is the sponsor
of this study.
Inclusion Criteria:
- Metastatic breast cancer (meaning the cancer has spread beyond its original location)
- At least one measurable lesion by CT or MRI
- Progression of disease following previous therapy for breast cancer
- Have received previous treatment with anthracyclines (e.g. doxorubicin[Adriamycin or
Doxil] or epirubicin [Ellence]), taxanes (paclitaxel [Taxol or Abraxane] or docetaxel
[taxotere]) for your breast cancer
- Not be pregnant
- Additional criteria to be determined at screening visit.
Exclusion Criteria:
- More than 3 previous chemotherapy regimens
- More than one treatment with non cytotoxic agents for breast cancer therapy (e.g.
herceptin [trastuzumab] or Avastin [bevacizumab)
- Prior treatment with epothilones (e.g. Ixabepilone)
- Symptomatic brain metastases
- Additional criteria to be determined at screening visit
We found this trial at
22
sites
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