This Trial, Evaluating the Long-term Safety and Tolerability of Brivaracetam Will Provide Subjects Suffering From Epilepsy, Who May Have Benefited From Brivaracetam as Adjunctive Treatment, the Opportunity to Receive Open Label Brivaracetam Treatment



Status:Completed
Conditions:Neurology, Epilepsy
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:16 - Any
Updated:12/7/2018
Start Date:January 2006
End Date:September 2017

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An Open-label, Multi-center, Follow-up Trial to Evaluate Long Term Safety and Efficacy of Brivaracetam Used as Adjunctive Treatment at a Flexible Dose up to a Maximum of 200 mg/Day in Subjects Aged 16 Years or Older Suffering From Epilepsy

This trial, evaluating the long-term safety and tolerability of brivaracetam will provide
subjects suffering from epilepsy, who may have benefited from brivaracetam as adjunctive
treatment, the opportunity to receive open label brivaracetam treatment.

Study access was limited to subjects having completed one of the previous brivaracetam (BRV)
studies: N01193 [NCT00175825], N01252 [NCT00490035], N01253 [NCT00464269], N01254
[NCT00504881].

Inclusion Criteria:

- Male/ female subjects from 16 years and on. Subjects under 18 years may only be
included where legally permitted and ethically accepted

- Subjects with epilepsy who have participated in previous brivaracetam trials which
allow access to the present study

- Subjects for whom the investigator believes a reasonable benefit from the long term
administration of brivaracetam may be expected

- Female subjects without childbearing potential. Female subjects with child bearing
potential are eligible if they use a medically accepted contraceptive method for the
duration of the study

- Subject/ legally acceptable representative considered as reliable and capable of
adhering to the protocol, visit schedule or medication intake according to the
judgment of the Investigator

Exclusion Criteria:

- Severe medical, neurological and psychiatric disorders or laboratory values which may
have an impact on the safety of the subject

- Poor compliance with the visit schedule or medication intake in the previous
brivaracetam study

- Pregnant or lactating women

- Participation in any clinical study of another investigational drug or device during
the study
We found this trial at
47
sites
1054 South Ohio Avenue
Columbus, Ohio 43206
1962
mi
from 91732
Columbus, OH
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Atlanta, Georgia
1919
mi
from 91732
Atlanta, GA
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Augusta, Georgia
2059
mi
from 91732
Augusta, GA
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1373 Maryland Avenue
Baltimore, Maryland 21201
2301
mi
from 91732
Baltimore, MD
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Bethesda, Maryland 20814
2277
mi
from 91732
Bethesda, MD
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1077 Massachusetts Avenue
Burlington, Massachusetts 02420
2570
mi
from 91732
Burlington, MA
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Charlottesville, Virginia
2208
mi
from 91732
Charlottesville, VA
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Chatswood, New South Wales 2067
7512
mi
from 91732
Chatswood,
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Chesterfield, Missouri
1552
mi
from 91732
Chesterfield, MO
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Chicago, Illinois
1728
mi
from 91732
Chicago, IL
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1366 Ohio River Scenic Byway
Cincinnati, Ohio 45202
1880
mi
from 91732
Cincinnati, OH
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1084 Texas Circle
Dallas, Texas 75182
1236
mi
from 91732
Dallas, TX
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Dallas, Texas
1223
mi
from 91732
Dallas, TX
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1391 Michigan Avenue
Detroit, Michigan 48226
1965
mi
from 91732
Detroit, MI
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1395 Michigan Avenue
Detroit, Michigan 48226
1965
mi
from 91732
Detroit, MI
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1078 West California Avenue
Fresno, California 93706
209
mi
from 91732
Fresno, CA
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Grand Rapids, Michigan
1839
mi
from 91732
Grand Rapids, MI
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Great Falls, Montana
990
mi
from 91732
Great Falls, MT
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2 Exchange Street
Greenville, South Carolina 29605
2020
mi
from 91732
Greenville, SC
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Houston, Texas
1358
mi
from 91732
Houston, TX
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1364 Lexington Road
Lexington, Kentucky 40422
1869
mi
from 91732
Lexington, KY
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1050 Arkansas River Trail
Little Rock, Arkansas 72201
1463
mi
from 91732
Little Rock, AR
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1380 West Kentucky Street
Louisville, Kentucky 40210
1811
mi
from 91732
Louisville, KY
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1369 West Wisconsin Avenue
Milwaukee, Wisconsin 53233
1727
mi
from 91732
Milwaukee, WI
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1061 Tennessee 6
Nashville, Tennessee 37203
1763
mi
from 91732
Nashville, TN
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1053 New York Avenue
New York, New York 11203
2436
mi
from 91732
New York, NY
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1392 California 1
Newport Beach, California 92660
32
mi
from 91732
Newport Beach, CA
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1052 Kentucky Avenue
Paducah, Kentucky 42003
1658
mi
from 91732
Paducah, KY
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1055 East Pennsylvania Boulevard
Philadelphia, Pennsylvania 19053
2382
mi
from 91732
Philadelphia, PA
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1059 East Pennsylvania Boulevard
Philadelphia, Pennsylvania 19053
2382
mi
from 91732
Philadelphia, PA
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1051 East Phoenix Street
Phoenix, Arizona 85541
383
mi
from 91732
Phoenix, AZ
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1362 Phoenix Bypass Route
Phoenix, Arizona 85337
316
mi
from 91732
Phoenix, AZ
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1359 Portland Street
Portland, Oregon 43616
1940
mi
from 91732
Portland, OR
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1393 Virginia Avenue
Richmond, Virginia 94804
360
mi
from 91732
Richmond, VA
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1365 Rochester Avenue
Rochester, New York 11213
2437
mi
from 91732
Rochester, NY
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1083 West Louisiana Avenue
Ruston, Louisiana 71270
1465
mi
from 91732
Ruston, LA
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1352 Lake Saint Louis Boulevard
Saint Louis, Missouri 63367
1543
mi
from 91732
Saint Louis, MO
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1389 Minnesota 5
Saint Paul, Minnesota 55102
1514
mi
from 91732
Saint Paul, MN
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Salt Lake City, Utah
570
mi
from 91732
Salt Lake City, UT
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1087 California Street
San Francisco, California 94108
355
mi
from 91732
San Francisco, CA
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1368 California Street
San Francisco, California 94109
355
mi
from 91732
San Francisco, CA
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1376 South Washington Street
Seattle, Washington 98144
960
mi
from 91732
Seattle, WA
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Springfield, Illinois
1608
mi
from 91732
Springfield, IL
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Toms River, New Jersey
2426
mi
from 91732
Toms River, NJ
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1374 West Cll Arizona
Tucson, Arizona 85705
424
mi
from 91732
Tucson, AZ
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Tupelo, Mississippi
1669
mi
from 91732
Tupelo, MS
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1375 South Kansas Street
Wichita, Kansas 67211
1182
mi
from 91732
Wichita, KS
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