E-Cigarettes and SNA
| Status: | Recruiting |
|---|---|
| Conditions: | Smoking Cessation, Tobacco Consumers |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 21 - 45 |
| Updated: | 1/26/2019 |
| Start Date: | April 2015 |
| End Date: | December 2022 |
| Contact: | Holly R Middlekauff, MD |
| Email: | hmiddlekauff@mednet.ucla.edu |
| Phone: | 310-206-6672 |
The Effects of Electronic Cigarettes on Sympathetic Nerve Activity and Oxidative Stress
Randomized controlled trial of electronic cigarettes with nicotine, without nicotine, and
sham control, on sympathetic nerve activity and markers of oxidative stress.
sham control, on sympathetic nerve activity and markers of oxidative stress.
Participants will use an electronic cigarette on 3 occasions: 1) with nicotine, 2) without
nicotine, 3) sham control, and measures of autonomic tone, including heart rate variability
(HRV) and sympathetic nerve activity (MSNA: microneurography), and oxidative stress will be
measured pre and post exposure.
nicotine, 3) sham control, and measures of autonomic tone, including heart rate variability
(HRV) and sympathetic nerve activity (MSNA: microneurography), and oxidative stress will be
measured pre and post exposure.
Inclusion Criteria:
Healthy
Exclusion Criteria:
- Cardiac disease
- Respiratory disease
- Diabetes mellitus
We found this trial at
1
site
Los Angeles, California 90095
Principal Investigator: Holly R Middlekauff, MD
Phone: 310-206-6672
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