Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
| Status: | Completed |
|---|---|
| Conditions: | Post-Surgical Pain, Orthopedic, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/6/2018 |
| Start Date: | May 2015 |
| End Date: | May 1, 2017 |
Comparing Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol Administration for Carpal Tunnel Release and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of
IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and
distal radius fracture patients.
IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and
distal radius fracture patients.
The study population will include patients presenting for surgery with carpal tunnel syndrome
as well as surgical treatment of distal radius fracture. Patients will be treated
intra-operatively with either IV tylenol, IV toradol, both, or neither. All patients will
receive the standard post-operative prescriptions for pain management. Daily pain surveys
scoring pain from 0-10 will be distributed to the subjects to be filled out over the course
of 10 days prior to first post-operative visit, usually 10-14 days later. Number of pain
pills used before the first post-operative visit will also be measured.
We hypothesize that the effects of intra-operative administration of IV tylenol and/or IV
toradol will have a significant effect on decreasing post-operative pain in the first 10 days
following distal radius fracture surgeries, with a significant difference in pain described
as at least a 2 points on a 0-10 pain scale.
We also hypothesize that intra-operative administration of IV tylenol and/or IV toradol will
not have such significant effect on decreasing post-operative pain for carpal tunnel release
surgery.
A secondary aim is to evaluate the post-operative opioid consumption of patients within these
treatment groups. We hypothesize that opioid consumption will be decreased in the groups
receiving IV tylenol and/or toradol for distal radius fracture surgery compared to the
placebo group. We do not expect such a difference for the carpal tunnel release surgery
group.
as well as surgical treatment of distal radius fracture. Patients will be treated
intra-operatively with either IV tylenol, IV toradol, both, or neither. All patients will
receive the standard post-operative prescriptions for pain management. Daily pain surveys
scoring pain from 0-10 will be distributed to the subjects to be filled out over the course
of 10 days prior to first post-operative visit, usually 10-14 days later. Number of pain
pills used before the first post-operative visit will also be measured.
We hypothesize that the effects of intra-operative administration of IV tylenol and/or IV
toradol will have a significant effect on decreasing post-operative pain in the first 10 days
following distal radius fracture surgeries, with a significant difference in pain described
as at least a 2 points on a 0-10 pain scale.
We also hypothesize that intra-operative administration of IV tylenol and/or IV toradol will
not have such significant effect on decreasing post-operative pain for carpal tunnel release
surgery.
A secondary aim is to evaluate the post-operative opioid consumption of patients within these
treatment groups. We hypothesize that opioid consumption will be decreased in the groups
receiving IV tylenol and/or toradol for distal radius fracture surgery compared to the
placebo group. We do not expect such a difference for the carpal tunnel release surgery
group.
Inclusion Criteria:
- carpal tunnel release surgery candidates,
- distal radius fracture surgery candidates
Exclusion Criteria:
- under 18 years of age,
- pregnant women,
- prisoners
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