A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1



Status:Enrolling by invitation
Conditions:Neurology, Neurology, Multiple Sclerosis
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:18 - 65
Updated:3/13/2019
Start Date:December 2015
End Date:December 2020

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A Phase 3 Open Label Study to Evaluate the Long-term Safety and Tolerability of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis

This study will evaluate the long-term safety and tolerability of ALKS 8700 for the treatment
of Relapsing Remitting Multiple Sclerosis (RRMS)


Inclusion Criteria:

- Has a confirmed diagnosis of RRMS

- Neurologically stable with no evidence of relapse within 30 days prior to Visit 2

- Additional criteria may apply

Exclusion Criteria:

- Subject is pregnant or breastfeeding or plans to become pregnant or begin
breastfeeding at any point during the study and for 30 days after any study drug
administration

- Diagnosis of primary progressive secondary progressive, or progressive relapsing MS

- History of clinically significant cardiovascular, pulmonary, gastrointestinal
(inflammatory bowel disease [IBD]; Crohn's disease, ulcerative colitis), dermatologic,
psychiatric, neurologic (other than MS), and/or other major disease that would
preclude participation in a clinical trial

- History of a myocardial infarction, including a silent myocardial infarction
identified on ECG, or unstable angina

- Additional criteria may apply
We found this trial at
56
sites
Detroit, Michigan 47201
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Albuquerque, New Mexico
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Albuquerque, NM
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Alexandria, Louisiana 71301
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Alexandria, LA
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Atlanta, Georgia 30308
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Atlanta, GA
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Atlantis, Florida 33462
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Atlantis, FL
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Basalt, Colorado 81621
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Basalt, CO
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Berkeley, California 94705
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Berkeley, CA
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Bradenton, Florida 34201
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Bradenton, FL
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Brugge,
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Canton, Ohio 44718
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Canton, OH
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Centennial, Colorado 80111
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Centennial, CO
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Charleston, South Carolina 29407
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Charleston, SC
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Charlotte, North Carolina 28204
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Charlotte, NC
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Columbus, Georgia 31904
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Columbus, GA
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Columbus, Ohio 43210
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Columbus, OH
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Cullman, Alabama 35058
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Cullman, AL
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Dallas, Texas 75231
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Dallas, TX
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Dayton, Ohio 45417
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Dayton, OH
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Denver, CO
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Des Moines, Iowa 50314
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Des Moines, IA
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Evanston, Illinois 60201
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Evanston, IL
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Franklin, Tennessee 37064
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Franklin, TN
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Golden Valley, Minnesota 55422
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Golden Valley, MN
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Greensboro, North Carolina 27405
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Greensboro, NC
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Greer, South Carolina 29650
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Greer, SC
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Houston, Texas 77007
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Houston, TX
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Indian Land, South Carolina 29707
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Indian Land, SC
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Knoxville, Tennessee 37922
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Knoxville, TN
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Lenexa, Kansas 66214
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Lenexa, KS
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Loma Linda, California 92354
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Loma Linda, CA
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Long Beach, California 90822
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Long Beach, CA
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Lubbock, Texas 79410
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Lubbock, TX
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Maitland, Florida 32751
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Maitland, FL
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Middlebury, Connecticut 06762
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Middlebury, CT
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Naples, Florida 34102
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Naples, FL
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Newport News, Virginia 23601
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Newport News, VA
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Oklahoma City, Oklahoma
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Oklahoma City, OK
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Ormond Beach, Florida 32174
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Ormond Beach, FL
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Patchogue, New York 11772
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Patchogue, NY
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Philadelphia, Pennsylvania 19131
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Philadelphia, PA
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Phoenix, AZ
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Raleigh, North Carolina 27612
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Raleigh, NC
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Richmond, Virginia 23228
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Richmond, VA
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Saint Louis, Missouri 63104
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Saint Louis, MO
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San Diego, California 92123
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San Diego, CA
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Sarasota, Florida 34239
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Sarasota, FL
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Seattle, Washington
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Seattle, WA
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Spartanburg, South Carolina 29307
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Spartanburg, SC
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Stamford, Connecticut 06905
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Stamford, CT
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Stony Brook, New York 11794
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Stony Brook, NY
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Syracuse, New York 13210
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Syracuse, NY
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Tampa, FL
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Tucson, Arizona 85712
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Tucson, AZ
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Vero Beach, Florida 32960
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Vero Beach, FL
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Washington, District of Columbia 20016
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Washington,
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Winston-Salem, North Carolina 27103
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Winston-Salem, NC
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