Home-Based Pulmonary Rehab for Patients With Pulmonary Fibrosis



Status:Completed
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:40 - Any
Updated:2/17/2019
Start Date:August 2015
End Date:March 16, 2018

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Outpatient (phase 2) pulmonary rehab is an important, but mostly underutilized intervention
to improve physical function in patients with idiopathic pulmonary fibrosis (IPF). Of those
individuals who complete phase 2 pulmonary rehab, only a small cohort continues with any type
of maintenance exercise therapy (phase 3). This is largely due to personal factors, such as
access to transportation, weather, scheduling difficulties, and cost.

Little is known about how to enhance physical activity among patients with IPF. In addition,
no studies have investigated the long-term maintenance strategies of physical training in
patients with IPF. Thus, the purpose of this study is to test the feasibility and
effectiveness of a home-based, pulmonary rehab program for patients with IPF. A randomized,
blinded, clinical trial (RCT) design with two arms -- Wii Fit Plus exergame program and
cognitive video gaming, with no active whole body movement involved — will be used to
investigate the benefits of a home-based exergame program on improving pulmonary-related
function and symptoms in patients with IPF.


Inclusion Criteria:

- confirmed diagnosis of IPF based on the criteria of the American Thoracic
Society/European Respiratory Society 2011 guidelines;

- ≥ 40 years-of-age;

- ambulatory without the use of an assistive device;

- stable clinical condition (i.e., no pulmonary exacerbation for at least 6 weeks);

- no changes in medication for at least 4 weeks before enrollment;

- currently sedentary (i.e., exercise or participate in sports less than 3 times per
week for 20 min in the past 6 months) and do not play any exergames;

- report dyspnea on exertion leading to a limitation in performing daily activities
(i.e., Medical Research Council (MRC) dyspnea grade >1);

- able to read and follow exercise directions in English on the television screen;

- have permission from their treating physician to participate in moderate-intensity
exercise;

- able to provide informed consent by understanding the nature of study participation.

Exclusion Criteria:

- contraindication for moderate-intensity exercise (e.g., unstable cardiac disease),

- severe musculoskeletal, vestibular, or neurological disorders limiting exercise
performance, or inability to perform the 6-min walk test or 15-step test,

- requires > 6 lpm supplemental oxygen therapy via nasal cannula during exercise to
maintain SpO2 >88%;

- MRC dyspnea grade 4 or 5; IPF patients with MRC dyspnea grade 4 or 5 have been
reported to show little or no improvement, or deteriorated following pulmonary rehab;

- stage 2 hypertension,

- anemia (hemoglobin < 8 g/dL);

- collagen vascular disease;

- obstructive lung disease,

- non-parenchymal restrictive lung disease,

- occupational lung disease (pneumoconiosis, hypersensitivity pneumonitis),

- sarcoidosis,

- other idiopathic interstitial pneumonia;

- currently participating or have participated (in the past 30 days) in another clinical
trial which can affect the outcomes of the proposed study; or

- planning to move out of Alabama within the next 6 months.
We found this trial at
1
site
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Phone: 205-934-6301
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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mi
from
Birmingham, AL
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