Gastrointestinal Microbiome Study of Appendiceal Cancer



Status:Recruiting
Healthy:No
Age Range:18 - 80
Updated:10/6/2018
Start Date:December 2015
End Date:December 2020
Contact:Michelle Sittig, RN
Email:msittig@mdmercy.com
Phone:410-332-9294

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Cohort Study of the Gastrointestinal Microbiome in Appendiceal Cancer With Peritoneal Spread

This study analyzes the gastrointestinal microbiome of appendiceal cancer patients with
peritoneal spread scheduled to undergo cytoreductive surgery with hyperthermic
intraperitoneal chemotherapy (CRS/HIPEC). Participants will provide fecal samples pre- and
post-operatively.

Analysis of the human microbiome is an attempt to define how changes in the human microbiome
are associated with health or disease.

Eligible participants scheduled to undergo cytoreductive surgery with hyperthermic
intraperitoneal chemotherapy (CRS/HIPEC) for appendiceal cancer will provide fecal samples
pre- and post-operatively. Investigators will analyze potential changes in the
gastrointestinal microbiome and make comparisons to an age-matched healthy sample.

Inclusion Criteria:

- Diagnosis of appendiceal cancer with peritoneal spread

- Candidate for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
(CRS/HIPEC)

- ≥18 and ≤ 80 years of age

- Eastern Cooperative Oncology Group performance status score of ≤2/Karnofsky
performance status (KPS) ≥70%

- Signed Institutional Review Board approved informed consent

Exclusion Criteria:

- <18 years of age

- Pregnant women

- Concurrent severe medical problems unrelated to malignancy
We found this trial at
1
site
Mercy Medical Center
345 St Paul Pl
Baltimore, Maryland 21202
(410) 332-9000
Mercy Medical Center "Mercy Medical Center" is a hospital located in Baltimore, Maryland. The landmark...
?
mi
from
Baltimore, MD
Click here to add this to my saved trials