Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair

The rationale for using prophylactic antibiotics after hypospadias surgery is to decrease the
occurrence of urinary tract infections (UTIs) and complications. However, even though
prophylactic antibiotics are used by some pediatric urologists, to date there has been no
evidence supporting the role of prophylactic antibiotics in decreasing UTIs or complications.
This is a prospective, randomized trial involving children undergoing distal or mid-shaft
hypospadias repair. Subjects randomized into a group taking prophylactic dosages of
antibiotics and a group not receiving post-operative antibiotics.

Inclusion Criteria:

- all children between ages 6 months to 2 years under going distal or mid shaft
hypospadias repair

- children of parents who give informed consent

- English speaking

- participant must be available for follow-up 3 and 12 months post-surgery

Exclusion Criteria:

- all proximal hypospadias and redo hypospadias repairs

- children who are allergic to sulfa medications

- patients who have UTI at time of surgery (proven by culture)