Dietary Nitrate and Physiological Aging



Status:Completed
Conditions:Healthy Studies
Therapuetic Areas:Other
Healthy:No
Age Range:60 - 85
Updated:10/14/2017
Start Date:October 2015
End Date:April 28, 2017

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Dietary Nitrate Supplementation and Physiological Function in Older Adults

The main purpose/s of this study is to examine the effects of 4 weeks of dietary nitrate
supplementation on peripheral chemoreceptor sensitivity, spontaneous baroreflex sensitivity,
and blood pressure responsiveness to a variety of physiological stressors in older healthy
adults. We will also examine the effect of dietary nitrate supplementation on measures of
central artery stiffness and aortic blood pressure in older adults.


Inclusion Criteria:

- Healthy older adults 60-85 years of age

Exclusion Criteria:

- Hypertension, hyperlipidemia, current smoker or smoker within the last year, heart
disease, diabetes, Chronic obstructive pulmonary disease, asthma, sleep apnea,
Raynaud's disease, body mass index (BMI) > 30 kg/m2, allergy medication, clinical
depression, autonomic disorders and other conditions or medications that might
normally alter cardiovascular function, exercise tolerance, and/or blood pressure
responses.
We found this trial at
1
site
101 Jessup Hall
Iowa City, Iowa 52242
(319) 335-3500
University of Iowa With just over 30,000 students, the University of Iowa is one of...
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Iowa City, IA
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