Optical Coherence Tomography of Tear Film Dynamics In-Vivo



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:4/22/2018
Start Date:November 2014
End Date:September 2017

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The purpose of this study is to evaluate a new instrument that takes digital images of tear
film (a thin film that coats the eye that is made up of oil and water). The investigators are
interested in measuring how the thickness of the tear film varies through time. The goal is
to develop a technique that may enable non-invasive evaluation of Dry Eye Disease for future
clinical diagnosis.


Inclusion Criteria:

- Clinically diagnosed Dry Eye Disease

- Normal individuals (those without a dry eye diagnosis and without eye abnormalities)

- Good general health (defined by medication use that has not changed within the last
month and the absence of medical conditions that are deemed confounding to the data as
determined by the PI)

- Ability to give informed consent

- Willing to spend time for the study

- Either gender

- Any racial or ethnic origin

Exclusion Criteria:

- Use of any prescription ocular medication (such as but not limited to, glaucoma
medications and Restasis) used within 14 days of the study visit

- Current eye disease, infection or inflammation that affects the surface of the eye
such as, but not limited to blepharitis and ocular allergy

- Past eye surgery, such as, but not limited to, refractive surgery. Subjects who have
had cataract surgery less than one year ago

- Use of soft or hard contact lenses 6 hours prior to visit

- Female subjects may not be pregnant or lactating (subjects will be asked to
self-report these conditions)

- Infectious diseases (for example, hepatitis, tuberculosis) or an immuno-suppressive
disease (for example, HIV) (subjects will be asked to self-report these conditions)
We found this trial at
1
site
60 Crittenden Blvd # 70
Rochester, New York 14642
(585) 275-2121
Phone: 585-276-4562
University of Rochester The University of Rochester is one of the country's top-tier research universities....
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Rochester, NY
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