Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia



Status:Completed
Conditions:Schizophrenia
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 60
Updated:8/3/2018
Start Date:September 2015
End Date:July 21, 2017

Use our guide to learn which trials are right for you!

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety and Tolerability of AVP-786 (Deuterated [d6]-Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) as an Adjunctive Treatment for Patients With Residual Schizophrenia.

The objectives of this 12-week study are to evaluate the efficacy, safety, and tolerability
of AVP-786 as an adjunctive treatment compared with placebo in patients with residual
schizophrenia.


Inclusion Criteria:

- Patients who meet DSM-IV-TR diagnostic criteria for schizophrenia using the M.I.N.I.
version 6.0.

- Patients must meet PANSS criteria

- Patients currently receiving atypical antipsychotics are eligible provided they are on
a stable dose

Exclusion Criteria:

- Patients with current major depressive disorder (MDD)

- Patients with extrapyramidal syndrome secondary to their ongoing antipsychotic
medication

- Patients currently using anticholinergic medications

- Recent in-patient hospitalization
We found this trial at
17
sites
?
mi
from
Orlando, FL
Click here to add this to my saved trials
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
?
mi
from
Augusta, GA
Click here to add this to my saved trials
?
mi
from
Boston, MA
Click here to add this to my saved trials
?
mi
from
Cerritos, CA
Click here to add this to my saved trials
?
mi
from
Chicago, IL
Click here to add this to my saved trials
?
mi
from
Garden Grove, CA
Click here to add this to my saved trials
?
mi
from
Grand Rapids, MI
Click here to add this to my saved trials
?
mi
from
Jamaica, NY
Click here to add this to my saved trials
?
mi
from
Marlton, NJ
Click here to add this to my saved trials
National City, California 91950
?
mi
from
National City, CA
Click here to add this to my saved trials
?
mi
from
New York, NY
Click here to add this to my saved trials
?
mi
from
Oakland, CA
Click here to add this to my saved trials
?
mi
from
Rochester, NY
Click here to add this to my saved trials
?
mi
from
San Diego, CA
Click here to add this to my saved trials
?
mi
from
Washington,
Click here to add this to my saved trials
?
mi
from
Worcester, MA
Click here to add this to my saved trials