Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia
| Status: | Completed |
|---|---|
| Conditions: | Schizophrenia |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 60 |
| Updated: | 8/3/2018 |
| Start Date: | September 2015 |
| End Date: | July 21, 2017 |
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety and Tolerability of AVP-786 (Deuterated [d6]-Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) as an Adjunctive Treatment for Patients With Residual Schizophrenia.
The objectives of this 12-week study are to evaluate the efficacy, safety, and tolerability
of AVP-786 as an adjunctive treatment compared with placebo in patients with residual
schizophrenia.
of AVP-786 as an adjunctive treatment compared with placebo in patients with residual
schizophrenia.
Inclusion Criteria:
- Patients who meet DSM-IV-TR diagnostic criteria for schizophrenia using the M.I.N.I.
version 6.0.
- Patients must meet PANSS criteria
- Patients currently receiving atypical antipsychotics are eligible provided they are on
a stable dose
Exclusion Criteria:
- Patients with current major depressive disorder (MDD)
- Patients with extrapyramidal syndrome secondary to their ongoing antipsychotic
medication
- Patients currently using anticholinergic medications
- Recent in-patient hospitalization
We found this trial at
17
sites
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